Ethyl (2S, 3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate, N-Oxide

Base Information

Chemical Name:Ethyl (2S, 3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate, N-Oxide
CAS No.:529474-73-5
Molecular Formula:C10H13NO5
Molecular Weight:227.21
Hs Code.:
DSSTox Substance ID:DTXSID40479832
Nikkaji Number:J1.853.243C
Wikidata:Q82314115
Mol file:529474-73-5.mol

Synonyms:529474-73-5;Ethyl (2S, 3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate, N-Oxide;ethyl (2S,3R)-2,3-dihydroxy-3-(1-oxidopyridin-1-ium-2-yl)propanoate;2-((1R,2S)-3-Ethoxy-1,2-dihydroxy-3-oxopropyl)pyridine 1-oxide;starbld0002283;DTXSID40479832;AKOS030242388

Suppliers and Price of Ethyl (2S, 3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate, N-Oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl(2S,3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate,N-Oxide
10mg
$ 395.00

TRC
Ethyl(2S,3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate,N-Oxide
2mg
$ 90.00

Total 1 raw suppliers

Chemical Property of Ethyl (2S, 3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate, N-Oxide

Chemical Property:

PSA：92.22000
LogP:0.07250
Storage Temp.:00C
Solubility.:Acetonitrile, Chloroform, Dichloromethane, Ethyl Acetate
XLogP3:-0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:227.07937252
Heavy Atom Count:16
Complexity:235

Purity/Quality:: Ethyl(2S,3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate,N-Oxide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C(C1=CC=CC=[N+]1[O-])O)O
Isomeric SMILES:CCOC(=O)[C@H]([C@@H](C1=CC=CC=[N+]1[O-])O)O
Uses Ethyl (2S, 3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate, N-Oxide (cas# 529474-73-5) is a compound useful in organic synthesis.

Technology Process of Ethyl (2S, 3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate, N-Oxide

There total 4 articles about Ethyl (2S, 3R)-2,3-Dihydroxy-3-(2-pyridinyl)propanoate, N-Oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 90922-50-2,259729-55-0
(E)-ethyl 3-(N-oxypyridin-2-yl)acrylate

: 503448-19-9,529474-73-5
(2R,3S)-ethyl 2,3-dihydroxy-3-(N-oxypyridin-2-yl)propanoate

Guidance literature:: With Hydroquinone 1,4-phthalazinediyl diether; K2; potassium hexacyanoferrate(III); In water; tert-butyl alcohol; for 24h;
DOI:10.1016/S0040-4039(02)02605-9

Reference yield: 75.0%

: 90922-50-2,259729-55-0
(E)-ethyl 3-(N-oxypyridin-2-yl)acrylate

: 529474-73-5
(2S,3R)-ethyl 2,3-dihydroxy-3-(N-oxypyridin-2-yl)propanoate

Guidance literature:: With K2; 1,4-bis(9-O-dihydroquinidine)phthalazine; potassium hexacyanoferrate(III); In water; tert-butyl alcohol; for 24h;
DOI:10.1016/S0040-4039(02)02605-9

Reference yield:

: 7340-23-0
ethyl 3-(pyridin-2-yl)acrylate

: 503448-19-9,529474-73-5
(2R,3S)-ethyl 2,3-dihydroxy-3-(N-oxypyridin-2-yl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 20 h / Heating

2: 39 percent / Ad-mix-α; MeSO2NH2 / 2-methyl-propan-2-ol; H2O / 24 h / 20 °C

With AD-mix-α; methanesulfonamide; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; water; tert-butyl alcohol;
DOI:10.1016/j.tet.2004.10.086