7340-23-0

Basic information

• Product Name: 2-Propenoic acid, 3-(2-pyridinyl)-, ethyl ester
• CAS NO: 7340-23-0
• Molecular Formula: C10H11NO2
• Molecular Weight: 177.203
• Mol File: 7340-23-0.mol
• Article Data: 50

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(2-pyridinyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(2-pyridinyl)-, ethyl ester(7340-23-0)
• EPA Substance Registry System: 2-Propenoic acid, 3-(2-pyridinyl)-, ethyl ester(7340-23-0)

Safety Data

• Hazardous Substances Data: 7340-23-0(Hazardous Substances Data)

Upstream product

• 54495-51-1 (E)-3-(2-pyridyl)acrylic acid 
• 7340-22-9 3-pyridin-2-yl-acrylic acid 
• 64-17-5 ethanol 
• 109-06-8 α-picoline 
• 609-09-6 Diethyl ketomalonate 
• 1121-60-4 pyridine-2-carbaldehyde 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 90922-50-2 (E)-ethyl 3-(N-oxypyridin-2-yl)acrylate 
• 110-86-1 pyridine 
• 623-47-2 propynoic acid ethyl ester 
• 140-88-5 ethyl acrylate 
• 2524-52-9 ethyl-2-picolinate 
• 5029-67-4 2-iodopyridine 

Downstream Products

• 4088-33-9 2-(2-Carboxy-ethyl)-piperidin 
• 2739-74-4 ethyl 3-(2-pyridinyl)propanoate 
• 99584-02-8 (E)-3-(pyridin-2-yl)acrylamide 
• 90922-50-2 (E)-ethyl 3-(N-oxypyridin-2-yl)acrylate 
• 131610-03-2 3-(pyridin-2-yl)prop-2-en-1-ol 
• 76132-63-3 (+/-)-3-phenyl-3-(pyridin-2-yl)propionic acid ethyl ester 
• 113985-52-7 (E)-3-(pyridin-2-yl)prop-2-en-1-ol 
• 25523-97-1 dexchlorpheniramine 

Relevant articles and documents

A One-Pot Synthesis of α,β-Unsaturated Esters From Esters

A convenient method for reductive Horner–Wadsworth–Emmons (HWE) olefination is described. The E-selective HWE homologation of various esters to α,β-unsaturated esters was readily achieved and gave the desired products in good-to-moderate yields under mild conditions. The one-pot reaction proceeds through an in situ generated aldehyde, formed via the partial reduction of an ester with lithium diisobutyl-t-butoxyaluminum hydride. The formation of cyclized metal acetal and subsequent decompose to the aldehyde for the olefination was found to be a crucial step in this C2-carbon homologation protocol.

Gold-catalyzed partial hydrogenation of activated alkynes mediated by triphenylphosphine

Gold(I) can exhibit a cooperative effect with triphenylphosphine, accelerating the triphenylphosphine-mediated partial hydrogenation of activated alkynes. In this protocol, 3-arylpropiolates are selectively reduced to the Z -isomer when the aryl ring bears an electron-donor substituent, whereas 3-arylpropynones are reduced to the E-isomers.

Facile synthesis of α, β-unsaturated esters through a one-pot copper-catalyzed aerobic oxidation-Wittig reaction

An efficient one-pot synthesis of α, β-unsaturated esters through the aerobic oxidation – Wittig tandem reaction of alcohols and phosphorous ylide is developed. This new method operates under mild reaction conditions, and uses CuI/TEMPO (TEMPO = 2,2,6,6-tetramethylpiperidine-N-oxyl) as co-catalyst and air (O2) as the oxidant. It tolerates a wide range of functionalized benzylic alcohol and aliphatic alcohols.