1-(DIMETHYLAMINO)PYRROLE

Base Information

• Chemical Name: 1-(DIMETHYLAMINO)PYRROLE
• CAS No.: 78307-76-3
• Molecular Formula: C6H10 N2
• Molecular Weight: 110.159
• Hs Code.: 2933990090
• Mol file: 78307-76-3.mol

Synonyms:1-Dimethylaminopyrrole

Chemical Property of 1-(DIMETHYLAMINO)PYRROLE

Chemical Property:

• Vapor Pressure: 6.56mmHg at 25°C
• Melting Point: 52 °C
• Refractive Index: n20/D 1.48(lit.)
• Boiling Point: 138-140 °C(lit.)
• PKA: -4.16±0.16(Predicted)
• Flash Point: 98 °F
• PSA: 8.17000
• Density: 0.912 g/mL at 25 °C(lit.)
• LogP: 0.68570
• Storage Temp.: Flammables area

Purity/Quality:

98%Min ^*data from raw suppliers

1-(Dimethylamino)pyrrole 99% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 10-36/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 1-(DIMETHYLAMINO)PYRROLE

There total 2 articles about 1-(DIMETHYLAMINO)PYRROLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

alpha-cedrene (469-61-4) → 2-(N,N-dimethylaminomethyl)pyrrole (14745-84-7) + pyrrole (109-97-7,30604-81-0) + N,N-dimethyl-1H-pyrrol-1-amine (78307-76-3)

Guidance literature:

With sodium hydroxide; for 24h; Heating;

DOI:10.1002/hlca.19830660626

Reference yield:

Trimethyl(1-pyrrrolyl)ammonium-p-toluolsulfonat + malonic acid dimethyl ester (108-59-8) → methyl-malonic acid dimethylester (609-02-9) + N,N-dimethyl-1H-pyrrol-1-amine (78307-76-3) + 1-<(Dimethylamino)methyl>pyrrol

Guidance literature:

With sodium hydride; Yield given. Multistep reaction. Yields of byproduct given; 1.) DME; 2.) DME, 20 deg C, 3 h; 3.) 50 deg C, 5 h; 4.) reflux, 14 h;

DOI:10.1002/hlca.19830660626

Reference yield: 99.0%

N,N-dimethyl-1H-pyrrol-1-amine (78307-76-3) → pyrrole (109-97-7,30604-81-0)

Guidance literature:

at 850 ℃; for 0.316667h; under 0.032 - 0.073 Torr; Temperature; Pressure;

DOI:10.24820/ark.5550190.p011.257

upstream raw materials:

alpha-cedrene

malonic acid dimethyl ester

Downstream raw materials:

3,4,5,6-Tetrachloro-6-(1-dimethylamino-1H-pyrrol-2-yl)-2-hydroxy-cyclohexa-2,4-dienone

2-(N,N-dimethylaminomethyl)pyrrole

Dimethyl-[2-((E)-styryl)-pyrrol-1-yl]-amine

N-dimethylamino-2-(3-nitrophenyl)pyrrole

Refernces