4-(Propan-2-yl)-3,4-dihydro[1,1'-biphenyl]-4-amine

Base Information

Chemical Name:4-(Propan-2-yl)-3,4-dihydro[1,1'-biphenyl]-4-amine
CAS No.:5730-84-7
Molecular Formula:C15H17N
Molecular Weight:211.307
Hs Code.:
DSSTox Substance ID:DTXSID50700780
Mol file:5730-84-7.mol

Synonyms:5730-84-7;4-(Propan-2-yl)-3,4-dihydro[1,1'-biphenyl]-4-amine;DTXSID50700780

Suppliers and Price of 4-(Propan-2-yl)-3,4-dihydro[1,1'-biphenyl]-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-(Propan-2-yl)-3,4-dihydro[1,1'-biphenyl]-4-amine

Chemical Property:

PSA：26.02000
LogP:4.08370
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:213.151749610
Heavy Atom Count:16
Complexity:295

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)C1(CC=C(C=C1)C2=CC=CC=C2)N

Technology Process of 4-(Propan-2-yl)-3,4-dihydro[1,1'-biphenyl]-4-amine

There total 10 articles about 4-(Propan-2-yl)-3,4-dihydro[1,1'-biphenyl]-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 16152-51-5
(4-isopropylphenyl)boronic acid

: 106-40-1
4-bromo-aniline

: 5730-84-7
4'-isopropyl-4-aminobiphenyl

Guidance literature:: With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 100 ℃; for 17h;
DOI:10.1021/jm070435y

Reference yield:

: 279242-10-3
4'-isopropyl-4-nitrobiphenyl

: 5730-84-7
4'-isopropyl-4-aminobiphenyl

Guidance literature:: With tin(ll) chloride; In ethanol; ethyl acetate; Heating;
DOI:10.1016/S1383-5718(01)00345-X

Reference yield:

: 586-61-8
4-iso-propylbromobenzene

: 5730-84-7
4'-isopropyl-4-aminobiphenyl

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-BuLi / hexane; tetrahydrofuran / 1 h / -78 °C

1.2: triisopropylborate / hexane; tetrahydrofuran / 2 h / 20 °C

1.3: 91 percent / Ba(OH)2*8H₂O; Pd(PPh₃)4 / hexane; tetrahydrofuran; 1,2-dimethoxy-ethane / 80 °C

2.1: SnCl₂*2H₂O / ethanol; ethyl acetate / Heating

With n-butyllithium; tin(ll) chloride; In tetrahydrofuran; ethanol; hexane; ethyl acetate;
DOI:10.1016/S1383-5718(01)00345-X