(S)-aminoglutethimide

Base Information

Chemical Name:(S)-aminoglutethimide
CAS No.:57288-03-6
Molecular Formula:C13H16N2O2
Molecular Weight:232.282
Hs Code.:
European Community (EC) Number:637-209-7
UNII:5S1T2OED7F
Nikkaji Number:J231.951I
Wikidata:Q27124214
Metabolomics Workbench ID:58761
ChEMBL ID:CHEMBL1394757
Mol file:57288-03-6.mol

Synonyms:(S)-aminoglutethimide;(S)-(-)-Aminoglutethimide;57288-03-6;(-)-Aminoglutethimide;D-Aminoglutethimide;(3S)-3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione;Aminoglutethimide, (S)-;(S)-()-Aminoglutethimide;(-)-(S)-Aminoglutethimide;5S1T2OED7F;2,6-Piperidinedione, 3-(4-aminophenyl)-3-ethyl-, (3S)-;CHEMBL1394757;CHEBI:53790;NCGC00016379-01;CAS-125-84-8;Lopac-A-9657;UNII-5S1T2OED7F;SCHEMBL116988;(S)-(-)-Aminoglutethimide, 97%;BDBM50406640;NCGC00015110-01;F89425;EN300-22161023;Q27124214

Suppliers and Price of (S)-aminoglutethimide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(S)-(?)-Aminoglutethimide 97%
500mg
$ 156.00

Total 4 raw suppliers

Chemical Property of (S)-aminoglutethimide

Chemical Property:

Vapor Pressure:1.5E-08mmHg at 25°C
Melting Point:115.5-119.5 °C(lit.)
Refractive Index:1.566
Boiling Point:457.4°C at 760 mmHg
Flash Point:230.4°C
PSA：72.19000
Density:1.173g/cm³
LogP:2.26320
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:232.121177757
Heavy Atom Count:17
Complexity:321

Purity/Quality:

98%,99%, ^*data from raw suppliers

(S)-(?)-Aminoglutethimide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N
Isomeric SMILES:CC[C@]1(CCC(=O)NC1=O)C2=CC=C(C=C2)N
Uses (S)-(?)-Aminoglutethimide can be used:As an internal standard in the separation of the pyridoglutethimide enantiomers using the HPLC technique.In the study of steroid hormones role on human cytomegalovirus replication in adrenocortical cells.

Technology Process of (S)-aminoglutethimide

There total 4 articles about (S)-aminoglutethimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 125-84-8
aminoglutethimide

: 55511-44-9
(+)₄₀₄-3-(4-aminophenyl)-3-ethyl-2,6-piperidinedione

: 57288-03-6
(-)-3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione

Guidance literature:: With Chiral Pack IA; In tetrahydrofuran; hexane; at 25 ℃; Product distribution / selectivity; Resolution of racemate;

Reference yield:

: (S)-(-)-3-ethyl-3-(4-nitrophenyl)piperidine-2,6-dione

: 57288-03-6
(-)-3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; for 1.5h; Ambient temperature;
DOI:10.1016/S0040-4020(97)00464-X

Reference yield:

: (S)-(+)-4-cyano-4-(4-nitrophenyl)hexanoic acid

: 57288-03-6
(-)-3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / H₂SO₄ / acetic acid / 2 h / 95 °C

2: H₂ / Pd-C / ethyl acetate / 1.5 h / Ambient temperature

With sulfuric acid; hydrogen; palladium on activated charcoal; In acetic acid; ethyl acetate;
DOI:10.1016/S0040-4020(97)00464-X