3-Furan-3-YL-propionaldehyde

Base Information

• Chemical Name: 3-Furan-3-YL-propionaldehyde
• CAS No.: 56859-93-9
• Molecular Formula: C7H8O2
• Molecular Weight: 124.139
• DSSTox Substance ID: DTXSID10451564
• Wikidata: Q82271640
• Mol file: 56859-93-9.mol

Synonyms:3-FURAN-3-YL-PROPIONALDEHYDE;56859-93-9;3-(FURAN-3-YL)PROPANAL;3-(3-furyl)propanal;4-n-Propylphenylaceticacid;3-(3-furyl)propionaldehyde;SCHEMBL1442395;DTXSID10451564;CTKLUTOJDZGYAS-UHFFFAOYSA-N;AKOS006331896;EN300-1234515

Chemical Property of 3-Furan-3-YL-propionaldehyde

Chemical Property:

• PSA: 30.21000
• LogP: 1.41110
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 124.052429494
• Heavy Atom Count: 9
• Complexity: 90.9

Purity/Quality:

98% ^*data from raw suppliers

3-FURAN-3-YL-PROPIONALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC=C1CCC=O

Technology Process of 3-Furan-3-YL-propionaldehyde

There total 9 articles about 3-Furan-3-YL-propionaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-(3-furanyl)propan-1-ol (56859-92-8) → 3-(furan-3-yl)propionaldehyde (56859-93-9)

Guidance literature:

With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane; at -78 - 20 ℃;

DOI:10.1021/jacs.1c08615

Reference yield: 80.0%

carbon monoxide (201230-82-2) + 3-ethenylfuran (67364-02-7) → (2R)-2-(furan-3-yl)propanal + 3-(furan-3-yl)propionaldehyde (56859-93-9)

Guidance literature:

With chiral binaphthalenedioxaphoshepin derivative; hydrogen; acetylacetonatodicarbonylrhodium(l); In benzene; at 60 ℃; for 6h;

DOI:10.1002/hlca.200690166

Reference yield: 68.0%

ethyl 3-(furan-3-yl)propanoate (56859-91-7) → 3-(furan-3-yl)propionaldehyde (56859-93-9)

Guidance literature:

With diisobutylaluminium hydride; In diethyl ether; dichloromethane; at -70 ℃; for 0.75h;

DOI:10.1021/jo050336x

upstream raw materials:

ethyl 3-(furan-3-yl)propanoate

3-(3-furanyl)propan-1-ol

carbon monoxide

3-ethenylfuran

Downstream raw materials:

perillenal

3-[3-(2,3-dimethoxyphenoxy)-4-methylpent-4-enyl]furan

3-((3E,7E,11E)-4,8,12,16-tetramethyl-6-(phenylsulfonyl)heptadeca-3,7,11,15-tetraen-1-yl)furan

3-((3E,7E,11E)-8,12,16-trimethyl-6-(phenylsulfonyl)heptadeca-3,7,11,15-tetraen-1-yl)furan