2,2-Dichloro-1-methyl-cyclopropanecarbonyl chloride

Base Information

• Chemical Name: 2,2-Dichloro-1-methyl-cyclopropanecarbonyl chloride
• CAS No.: 56447-09-7
• Molecular Formula: C5H5Cl3O
• Molecular Weight: 187.453
• Hs Code.: 2916209090
• European Community (EC) Number: 673-240-2
• DSSTox Substance ID: DTXSID30374185
• Nikkaji Number: J2.210.505A
• Mol file: 56447-09-7.mol

Synonyms:56447-09-7;2,2-Dichloro-1-methyl-cyclopropanecarbonyl chloride;2,2-dichloro-1-methylcyclopropane-1-carbonyl chloride;2,2-dichloro-1-methylcyclopropanecarbonyl chloride;2,2-dichloro-1-methyl-cyclopropanecarbonylchloride;SCHEMBL1136246;DTXSID30374185;AUVFGQDYJGWIJS-UHFFFAOYSA-N;CYCLOPROPANECARBONYL CHLORIDE, 2,2-DICHLORO-1-METHYL- (9CI);AKOS006276410;AT27996;BB 0221138;2,2-dichloro-1-methylcyclopropanecarbonylchloride;1-Methyl-2,2-dichlorocyclopropanecarbonyl chloride;cyclopropanecarbonyl chloride,2,2-dichloro-1-methyl-;1-methyl-2,2-dichlorocyclopropanecarboxylic acid chloride;Cyclopropanecarbonyl chloride,2,2-dichloro-1-methyl-(9ci)

Chemical Property of 2,2-Dichloro-1-methyl-cyclopropanecarbonyl chloride

Chemical Property:

• Vapor Pressure: 0.247mmHg at 25°C
• Refractive Index: 1.514
• Boiling Point: 205.7°C at 760 mmHg
• Flash Point: 81.1°C
• PSA: 17.07000
• Density: 1.49g/cm³
• LogP: 2.33570
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 185.940598
• Heavy Atom Count: 9
• Complexity: 166

Purity/Quality:

97% ^*data from raw suppliers

CYCLOPROPANECARBONYLCHLORIDE,2,2-DICHLORO-1-METHYL- 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CC1(Cl)Cl)C(=O)Cl

Technology Process of 2,2-Dichloro-1-methyl-cyclopropanecarbonyl chloride

There total 2 articles about 2,2-Dichloro-1-methyl-cyclopropanecarbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,2-dichloro-1-methylcyclopropanecarboxylic acid (1447-14-9) → 2,2-dichloro-1-methyl-cyclopropanoyl chloride (56447-09-7)

Guidance literature:

With thionyl chloride; for 3h; Heating;

DOI:10.1007/BF00699840

Reference yield:

→ 2,2-dichloro-1-methyl-cyclopropanoyl chloride (56447-09-7)

Guidance literature:

Reference yield: 97.0%

2,2-dichloro-1-methyl-cyclopropanoyl chloride (56447-09-7) + 1-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylthio)phenyl]piperazine → 1-(2,2-dichloro-1-methylcyclopropanecarbonyl)-4-[2-fluoro-4-methyl-5-(2,2,2-trifluoroethylthio)phenyl]piperazine

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h;

upstream raw materials:

2,2-dichloro-1-methylcyclopropanecarboxylic acid

Downstream raw materials:

3-phenoxybenzyl 2,2-dichloro-1-methylcyclopropane-1-carboxylate

α(RS)-cyano-3-phenoxybenzyl 2,2-dichloro-1-methylcyclopropane-1-carboxylate

2,5,8-trimethyl-1-naphthol

(S*)-(4-chlorophenyl)(2,2-dichloro-1-methylcyclopropyl)methanone