2-Difluoromethoxytoluene

Base Information

Chemical Name:2-Difluoromethoxytoluene
CAS No.:42173-52-4
Molecular Formula:C8H8F2O
Molecular Weight:158.15
Hs Code.:2909309090
DSSTox Substance ID:DTXSID30382588
Nikkaji Number:J3.000.070F
Wikidata:Q82173948
Mol file:42173-52-4.mol

Synonyms:2-Difluoromethoxytoluene;42173-52-4;2-(Difluoromethoxy)toluene;1-(difluoromethoxy)-2-methylbenzene;MFCD06246896;SCHEMBL1911968;DTXSID30382588;UZMXDPPOKPYMPR-UHFFFAOYSA-O;ZVIWTWHIBTWACW-UHFFFAOYSA-N;AKOS006228544;AS-48127;CS-0121262;FT-0677370;F18875

Suppliers and Price of 2-Difluoromethoxytoluene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-(Difluoromethoxy)toluene
5 g
$ 395.00

Matrix Scientific
2-(Difluoromethoxy)toluene 97%
5g
$ 32.00

Matrix Scientific
2-(Difluoromethoxy)toluene 97%
1g
$ 11.00

Matrix Scientific
2-(Difluoromethoxy)toluene 97%
25g
$ 90.00

American Custom Chemicals Corporation
2-DIFLUOROMETHOXYTOLUENE 95.00%
5G
$ 1206.98

Alichem
2-(Difluoromethoxy)toluene
1g
$ 1564.50

Alichem
2-(Difluoromethoxy)toluene
500mg
$ 847.60

Alichem
2-(Difluoromethoxy)toluene
250mg
$ 499.20

AK Scientific
2-(Difluoromethoxy)toluene
1g
$ 64.00

Total 15 raw suppliers

Chemical Property of 2-Difluoromethoxytoluene

Chemical Property:

Vapor Pressure:3.19mmHg at 25°C
Refractive Index:1.4548 (20℃)
Boiling Point:74-76℃ (45 Torr)
Flash Point:56.6°C
PSA：9.23000
Density:1.121g/cm³
LogP:2.59640
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:158.05432120
Heavy Atom Count:11
Complexity:117

Purity/Quality:

99%, ^*data from raw suppliers

2-(Difluoromethoxy)toluene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1OC(F)F

Technology Process of 2-Difluoromethoxytoluene

There total 4 articles about 2-Difluoromethoxytoluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 83190-00-5
1-difluoromethoxy-2-methyl-4-nitrobenzene

2-(difluoromethoxy)-1-methyl-4-nitrobenzene: 2-(difluoromethoxy)-1-methyl-4-nitrobenzene

: 42173-52-4
difluoromethyl 2-methylphenyl ether

Guidance literature:: With nitric acid;

Reference yield:

: 1-(difluoromethoxy)-3-methyl-6-nitro-4-(trifluoromethyl)-1H-benzo[d][1,2,3]triazol-3-ium trifluoromethanesulfonate

: 108-88-3,15644-74-3,16713-13-6
toluene

: 42173-52-4
difluoromethyl 2-methylphenyl ether

: 1583-83-1
4-methyl-α,α-difluoroanisole

: 4837-15-4
1-(difluoromethoxy)-3-methylbenzene

Guidance literature:: With tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; In acetonitrile; at 23 ℃; for 12h; Overall yield = 66 %Spectr.; Irradiation;
DOI:10.1039/C8SC05390A

Reference yield:

: 529-20-4
2-methylphenyl aldehyde

: 42173-52-4
difluoromethyl 2-methylphenyl ether

: 1864-95-5
o-methylphenyl formate

Guidance literature:: With difluoro[4-(trifluoromethyl)phenyl]-λ³-bromane; In chloroform; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1021/ol202248x