N-(4-Fluorobenzyl)cyclopropanamine hydrochloride

Base Information

• Chemical Name: N-(4-Fluorobenzyl)cyclopropanamine hydrochloride
• CAS No.: 473732-87-5
• Molecular Formula: C10H12FN
• Molecular Weight: 165.2073832
• DSSTox Substance ID: DTXSID70589498
• Mol file: 473732-87-5.mol

Synonyms:N-(4-FLUOROBENZYL)CYCLOPROPANAMINE HYDROCHLORIDE;cyclopropyl(4-fluorobenzyl)amine hydrochloride;696589-27-2;N-[(4-fluorophenyl)methyl]cyclopropanamine;hydrochloride;N-[(4-fluorophenyl)methyl]cyclopropanamine hydrochloride;DTXSID70589498;MFCD07110865;AKOS015916673;EN300-7376375;N-[(4-Fluorophenyl)methyl]cyclopropanamine--hydrogen chloride (1/1)

Chemical Property of N-(4-Fluorobenzyl)cyclopropanamine hydrochloride

Chemical Property:

• PSA: 12.03000
• LogP: 3.27060
• Storage Temp.: 2-8°C(protect from light)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 201.0720553
• Heavy Atom Count: 13
• Complexity: 137

Purity/Quality:

97% ^*data from raw suppliers

(r)-cyclopropyl(4-fluorophenyl)methanaminehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1NCC2=CC=C(C=C2)F.Cl

Technology Process of N-(4-Fluorobenzyl)cyclopropanamine hydrochloride

There total 2 articles about N-(4-Fluorobenzyl)cyclopropanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

→ (R)-(4-fluorophenyl)(cyclopropyl)methanamine (473732-87-5,473732-88-6)

Guidance literature:

Reference yield:

α-cyclopropyl-4-fluorobenzylamine (705-14-6,473732-88-6) → (S)-cyclopropyl(4-fluorophenyl)methylamine (473732-88-6) + (R)-(4-fluorophenyl)(cyclopropyl)methanamine (473732-87-5,473732-88-6)

Guidance literature:

With Chiralpak AY-H; In diethylamine; acetonitrile; Purification / work up; Resolution of racemate;

upstream raw materials:

α-cyclopropyl-4-fluorobenzylamine