1-amino-2,3-dihydro-1H-inden-4-ol

Base Information

• Chemical Name: 1-amino-2,3-dihydro-1H-inden-4-ol
• CAS No.: 479206-20-7
• Molecular Formula: C9H11NO
• Molecular Weight: 149.18974
• Hs Code.: 2922199090
• European Community (EC) Number: 854-465-7
• ChEMBL ID: CHEMBL1189921
• Nikkaji Number: J2.331.763J
• Mol file: 479206-20-7.mol

Synonyms:1-amino-2,3-dihydro-1H-inden-4-ol;479206-20-7;1-Amino-indan-4-ol;SCHEMBL4202381;CHEMBL1189921;MFCD09947535;AKOS000193176;AKOS016905370;SB31671;SB32044;SB37311;CS-0452852;1H-Inden-4-ol,1-amino-2,3-dihydro-(9ci);EN300-67621;N11146;1H-Inden-4-ol, 1-amino-2,3-dihydro- (9CI);Z317054124

Chemical Property of 1-amino-2,3-dihydro-1H-inden-4-ol

Chemical Property:

• PSA: 46.25000
• LogP: 2.03850
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 149.084063974
• Heavy Atom Count: 11
• Complexity: 149

Purity/Quality:

≥99% ^*data from raw suppliers

1-amino-2,3-dihydro-1H-inden-4-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=C(C1N)C=CC=C2O

Technology Process of 1-amino-2,3-dihydro-1H-inden-4-ol

There total 3 articles about 1-amino-2,3-dihydro-1H-inden-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxy-2,3-dihydroindan-1-one (40731-98-4) → 1-amino-2,3-dihydro-1H-inden-4-ol (479206-20-7,1228561-05-4)

Guidance literature:

With ammonium acetate; sodium cyanoborohydride;

DOI:10.1021/jo052621m

Reference yield:

4-hydroxy-indan-1-one oxime (103441-70-9) → 1-amino-2,3-dihydro-1H-inden-4-ol (479206-20-7,1228561-05-4)

Guidance literature:

With hydrogen; platinum(IV) oxide; In acetic acid; under 2280 Torr; Yield given;

DOI:10.1021/jm00111a014

Reference yield:

4-hydroxy-indan-1-one oxime (103441-70-9) → 1-amino-2,3-dihydro-1H-inden-4-ol (479206-20-7,1228561-05-4)

Guidance literature:

With hydrogen;

DOI:10.1021/jo052621m

upstream raw materials:

4-hydroxy-indan-1-one oxime

4-hydroxy-indan-1-one oxime

4-hydroxy-2,3-dihydroindan-1-one

Downstream raw materials:

2-anilino-7-[(1S)-4-hydroxy-2,3-dihydro-1H-inden-1-yl]-5,5-dimethyl-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one