4-Methoxybenzamidine hydrochloride

Base Information

• Chemical Name: 4-Methoxybenzamidine hydrochloride
• CAS No.: 51721-68-7
• Molecular Formula: C8H11ClN2O
• Molecular Weight: 186.641
• Hs Code.: 2916310090
• European Community (EC) Number: 808-172-6
• ChEMBL ID: CHEMBL2286472
• DSSTox Substance ID: DTXSID30489602
• Mol file: 51721-68-7.mol

Synonyms:51721-68-7;4-Methoxybenzamidine hydrochloride;4-METHOXYBENZIMIDAMIDE HYDROCHLORIDE;4-METHOXYBENZAMIDINE, HYDROCHLORIDE;4-METHOXY-BENZAMIDINE HYDROCHLORIDE;4-methoxybenzene-1-carboximidamide hydrochloride;MFCD00466114;4-methoxybenzenecarboximidamide;hydrochloride;p-methoxy-benzamidine hydrochloride;4-Anisamidine Hydrochloride;4-Methoxybenzamidine HCl;4-methoxybenzenecarboximidamide hydrochloride;SCHEMBL2570665;CHEMBL2286472;p-methoxybenzamidine hydrochloride;DTXSID30489602;4-Methoxybenzamidine,hydrochloride;AJOSDIDPIBJFAI-UHFFFAOYSA-N;4-Methoxybenzamidine Monohydrochloride;4-methoxybenzamidine hydrochloride salt;AKOS016353295;AB06258;4-anisamidine hydrochloride, AldrichCPR;4-METHOXYBENZENECARBOXIMIDAMIDE HCL;4-METHOXYBENZIMIDAMIDEHYDROCHLORIDE;CS-10314;SY057349;CS-0042893;FT-0618910;M2612;EN300-115842;H10325;A828740;[amino-(4-methoxyphenyl)methylidene]azanium;chloride;4-Methoxybenzene-1-carboximidamide--hydrogen chloride (1/1)

Chemical Property of 4-Methoxybenzamidine hydrochloride

Chemical Property:

• Vapor Pressure: 0.0166mmHg at 25°C
• Melting Point: 218-220°C
• Boiling Point: 255.1°C at 760 mmHg
• Flash Point: 108.1°C
• PSA: 59.10000
• LogP: 2.58130
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility.: DMSO (Slightly), Water (Slightly)
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 186.0559907
• Heavy Atom Count: 12
• Complexity: 139

Purity/Quality:

98%Min ^*data from raw suppliers

4-Methoxybenzamidine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(=N)N.Cl
• Uses: 4-Methoxybenzamidine Hydrochloride (cas# 51721-68-7) is a compound useful in organic synthesis.

Technology Process of 4-Methoxybenzamidine hydrochloride

There total 6 articles about 4-Methoxybenzamidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C14H27LiN2OSi2 → 4-methoxybenzamidine hydrochloride (51721-68-7)

Guidance literature:

With hydrogenchloride; at 0 ℃;

DOI:10.1016/0022-328X(87)80017-7

Reference yield: 75.0%

ethyl 4-methoxybenzimidate hydrochloride (54998-29-7) → 4-methoxybenzamidine hydrochloride (51721-68-7)

Guidance literature:

With ammonia; In ethanol; at 60 ℃; for 3h;

Reference yield: 44.5%

4-methoxybenzonitrile (874-90-8) → 4-methoxybenzamidine hydrochloride (51721-68-7)

Guidance literature:

4-methoxybenzonitrile; With sodium methylate; In methanol; at 20 ℃; for 48h;

With ammonium chloride; In methanol; at 20 ℃; for 24h;

DOI:10.1016/j.ejmech.2018.03.018

upstream raw materials:

ethyl 4-methoxybenzimidate hydrochloride

4-methoxybenzonitrile

3-chloro-3-(4-methoxyphenyl)diaziridine

methyl 4-methoxybenzimidate hydrochloride

Downstream raw materials:

2-(p-methoxyphenyl)-5,6-pentamethylenepyrimidin-4(3H)-one

2-(p-methoxyphenyl)-hexamethylenepyrimidin-4(3H)-one

2-(p-methoxyphenyl)-5,6-decamethylenepyrimidin-4(3H)-one

2-<4-Tolyl>-6-<4-methoxy-phenylazo>-1,3-diaza-azulen