Technology Process of Benzenecarboximidic acid, 4-methoxy-, methyl ester, hydrochloride
There total 2 articles about Benzenecarboximidic acid, 4-methoxy-, methyl ester, hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
at -5 - 20 ℃;
for 27h;
- Guidance literature:
-
In
methanol; ice-water;
- Guidance literature:
-
methyl 4-methoxybenzimidate hydrochloride;
With
triethylamine;
In
dichloromethane;
at 20 ℃;
for 0.5h;
Inert atmosphere;
p-toluenesulfonyl chloride;
With
dmap;
In
dichloromethane;
for 72h;
Inert atmosphere;
Reflux;
DOI:10.1021/ol301194e