3-Hydroxymethyl Mefenamic Acid

Base Information

• Chemical Name: 3-Hydroxymethyl Mefenamic Acid
• CAS No.: 5129-20-4
• Molecular Formula: C15H15NO3
• Molecular Weight: 257.28
• Hs Code.: 2922509090
• Mol file: 5129-20-4.mol

Synonyms:2-[[3-(Hydroxymethyl)-2-methylphenyl]amino]-benzoic Acid;3-Hydroxymethyl Mefenamic Acid;N-(a3-Hydroxy-2,3-xylyl)-anthranilic Acid

Chemical Property of 3-Hydroxymethyl Mefenamic Acid

Chemical Property:

• Melting Point: 219-222°C
• Boiling Point: 454.9±45.0 °C(Predicted)
• PKA: 3.72±0.36(Predicted)
• PSA: 69.56000
• Density: 1.298±0.06 g/cm3(Predicted)
• LogP: 3.00210
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

3-Hydroxymethyl Mefenamic Acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Hydroxymethyl Mefenamic Acid

There total 2 articles about 3-Hydroxymethyl Mefenamic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

mefenamic Acid (61-68-7) → 4’-hydroxymefenamic acid (1631996-20-7) + 5-hydroxymefenamic acid (39062-59-4) + 3-Hydroxymethylmefenamic acid (5129-20-4)

Guidance literature:

With glucose-6-phosphate dehydrogenase; glucose-6-phosphate; ethylenediaminetetraacetic acid; cytochrome P₄₅₀ BM₃ mutant M₁₁; NADPH; magnesium chloride; In aq. phosphate buffer; at 4 ℃; pH=7.4; Temperature; regioselective reaction; Kinetics; Enzymatic reaction;

DOI:10.1002/cbic.201900751

Reference yield:

→ 3-Hydroxymethylmefenamic acid (5129-20-4)

Guidance literature:

o-Brombenzoesaeure, entspr. Aminobenzylalkohol/Cu;

upstream raw materials:

mefenamic Acid