5-hydroxymefenamic acid

Base Information

• Chemical Name: 5-hydroxymefenamic acid
• CAS No.: 39062-59-4
• Molecular Formula: C₁₅H₁₅NO₃
• Molecular Weight: 257.289

Synonyms:

Chemical Property of 5-hydroxymefenamic acid

Chemical Property:

Purity/Quality:

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Technology Process of 5-hydroxymefenamic acid

There total 2 articles about 5-hydroxymefenamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

mefenamic Acid (61-68-7) → 4’-hydroxymefenamic acid (1631996-20-7) + 5-hydroxymefenamic acid (39062-59-4) + 3-Hydroxymethylmefenamic acid (5129-20-4)

Guidance literature:

With glucose-6-phosphate dehydrogenase; glucose-6-phosphate; ethylenediaminetetraacetic acid; cytochrome P₄₅₀ BM₃ mutant M₁₁; NADPH; magnesium chloride; In aq. phosphate buffer; at 4 ℃; pH=7.4; Temperature; regioselective reaction; Kinetics; Enzymatic reaction;

DOI:10.1002/cbic.201900751

Reference yield:

mefenamic Acid (61-68-7) → 4’-hydroxymefenamic acid (1631996-20-7) + 5-hydroxymefenamic acid (39062-59-4)

Guidance literature:

With glucose-6-phosphate dehydrogenase; glucose-6-phosphate; ethylenediaminetetraacetic acid; recombinant human cytochrome P₄₅₀ 1A₂ (CYP₁A₂); NADPH; magnesium chloride; In aq. phosphate buffer; at 6.24 ℃; pH=7.4; Temperature; regioselective reaction; Kinetics; Enzymatic reaction;

DOI:10.1002/cbic.201900751

upstream raw materials:

mefenamic Acid

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