Benzyl (S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate

Base Information

Chemical Name:Benzyl (S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate
CAS No.:50888-84-1
Molecular Formula:C17H22N2O3
Molecular Weight:302.373
Hs Code.:2933990090
European Community (EC) Number:621-208-3
DSSTox Substance ID:DTXSID60350871
Nikkaji Number:J396.370E
ChEMBL ID:CHEMBL1088406
Mol file:50888-84-1.mol

Synonyms:50888-84-1;(S)-benzyl 2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate;Benzyl (S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate;benzyl (2S)-2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate;CHEMBL1088406;benzyl (S)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate;SCHEMBL6384850;DTXSID60350871;BDBM50316820;AKOS015891421;AS-71480;CS-0156227;D85676;A935505;Benzyl(S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate;Benzyl (S)-(-)-2-(1-pyrrolidinyl carbonyl)-1-pyrrolidinecarboxylate;Benzyl (S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate, 97%

Suppliers and Price of Benzyl (S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Benzyl (S)-(?)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate 97%
5g
$ 113.00

Crysdot
(S)-Benzyl2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate 95+%
25g
$ 549.00

Chem-Impex
Benzyl(S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate,≥97%(TLC) ≥97%(TLC)
5G
$ 118.81

Chemenu
benzyl(S)-2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate 95%
25g
$ 518.00

American Custom Chemicals Corporation
(S)-2-[(PYRROLIDIN-1-YL)CARBONYL]PYRROLIDINE-1-CARBOXYLIC ACID BENZYL ESTER 95.00%
1G
$ 210.00

Alichem
(S)-Benzyl2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate
10g
$ 400.00

Total 7 raw suppliers

Chemical Property of Benzyl (S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:132-135 °C(lit.)
Refractive Index:1.583
Boiling Point:485.6°Cat760mmHg
Flash Point:247.5°C
PSA：49.85000
Density:1.233g/cm³
LogP:2.28580
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:302.16304257
Heavy Atom Count:22
Complexity:401

Purity/Quality:

98%min ^*data from raw suppliers

Benzyl (S)-(?)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)C(=O)C2CCCN2C(=O)OCC3=CC=CC=C3
Isomeric SMILES:C1CCN(C1)C(=O)[C@@H]2CCCN2C(=O)OCC3=CC=CC=C3
Uses Benzyl (S)-(?)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate can be used as an intermediate in the preparation of:An organocatalyst, which is used in the Michael addition of cyclic ketones.Hydrazone-based?chiral auxiliary, which is used to prepare chiral ketones.

Technology Process of Benzyl (S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate

There total 5 articles about Benzyl (S)-(-)-2-(1-pyrrolidinylcarbonyl)-1-pyrrolidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 123-75-1
pyrrolidine

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 50888-84-1
(S)-benzyl 2-(pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1016/j.tetasy.2006.01.034