3-BETA,5-ALPHA-TETRAHYDRODEOSOXYCORTICOSTERONE

Base Information

Chemical Name:3-BETA,5-ALPHA-TETRAHYDRODEOSOXYCORTICOSTERONE
CAS No.:567-01-1
Molecular Formula:C₂₁H₃₄O₃
Molecular Weight:334.499
Hs Code.:
Mol file:567-01-1.mol

Synonyms:5-ALPHA-PREGNAN-3-BETA, 21-DIOL-20-ONE;3-BETA,5-ALPHA-TETRAHYDRODEOSOXYCORTICOSTERONE;5-A-pregnane-3-B-21-diol-20-one

Suppliers and Price of 3-BETA,5-ALPHA-TETRAHYDRODEOSOXYCORTICOSTERONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3β,5α-Tetrahydrodeoxycorticosterone
5mg
$ 55.00

TRC
3β,5α-Tetrahydrodeoxycorticosterone
250mg
$ 1635.00

Medical Isotopes, Inc.
3β,5α-Tetrahydrodeoxycorticosterone
10 mg
$ 650.00

Cayman Chemical
Epiallopregnanolone ≥95%
1mg
$ 28.00

Cayman Chemical
Epiallopregnanolone ≥95%
10mg
$ 108.00

Cayman Chemical
Epiallopregnanolone ≥95%
25mg
$ 237.00

Cayman Chemical
Epiallopregnanolone ≥95%
5mg
$ 61.00

ApexBio Technology
Epiallopregnanolone
25mg
$ 303.00

ApexBio Technology
Epiallopregnanolone
10mg
$ 139.00

ApexBio Technology
Epiallopregnanolone
5mg
$ 78.00

Total 8 raw suppliers

Chemical Property of 3-BETA,5-ALPHA-TETRAHYDRODEOSOXYCORTICOSTERONE

Chemical Property:

Melting Point:147.9 - 148.7 °C (methanol)
PSA：57.53000
LogP:3.56760
Solubility.:≤25mg/ml in ethanol;25mg/ml in DMSO;25mg/ml in dimethyl formamide

Purity/Quality:

99% ^*data from raw suppliers

3β,5α-Tetrahydrodeoxycorticosterone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description 3β,5α-THDOC is a neurosteroid. It inhibits seizures induced by pilocarpine, but not pentylenetetrazol (PTZ; ), in mice (ED50s = 45.9 and >100 mg/kg, respectively). 3β,5α-THDOC has been found in the urine of women during the third trimester of pregnancy.
Uses 3β,5α-Tetrahydrodeoxycorticosterone is a novel derivative of the steroid Dehydroepiandrosterone (DHEA), a known uncompetitive inhibitor of Glucose 6-Phosphate Dehydrogenase (G6PD). Studies have shown that 3β,5α-Tetrahydrodeoxycorticosterone may have potential function in the modulation of calcium and GABAA-gated chloride channel currents found in rat and guinea-pig neurons. 3β,5α-Tetrahydrodeoxycorticosterone is a novel derivative of the steroid Dehydroepiandrosterone (DHEA), a known uncompetitive inhibitor of Glucose 6-Phosphate Dehydrogenase (G6PD). Studies have shown that 3β,5α-Tetrahydrodeoxycorticosterone may have potential function in the modulation of calcium and GABAA-gated chloride channel currents found in rat and guinea-pig neurons.

Technology Process of 3-BETA,5-ALPHA-TETRAHYDRODEOSOXYCORTICOSTERONE

There total 14 articles about 3-BETA,5-ALPHA-TETRAHYDRODEOSOXYCORTICOSTERONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 51296-50-5,95341-20-1
(3β,5α)-21-bromo-3-hydroxypregnan-20-one

: 567-02-2,567-03-3,800-10-2,33995-21-0,51548-31-3,108450-73-3,567-01-1
(3β,5α)-3,21-dihydroxypregnan-20-one

Guidance literature:: With water; sodium hydroxide; for 0.5h;
DOI:10.1021/jm300317k

Reference yield: 44.0%

: 56-47-3
deoxycorticosterone acetate

: 567-02-2,567-03-3,800-10-2,33995-21-0,51548-31-3,108450-73-3,567-01-1
(3β,5α)-3,21-dihydroxypregnan-20-one

: 298-36-2
5α-pregnan-21-ol-3,20-dione

Guidance literature:: In ethanol; at 24 - 26 ℃; for 96h; Penicillium decumbens ATCC 10436, potato dextrose broth;
DOI:10.1016/0039-128X(95)00071-W