4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione

Base Information

Chemical Name:4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione
CAS No.:582-65-0
Molecular Formula:C10H6F4O2
Molecular Weight:234.15
Hs Code.:2914700090
European Community (EC) Number:688-034-8
DSSTox Substance ID:DTXSID60377947
Nikkaji Number:J907.878I
Wikidata:Q82167350
Mol file:582-65-0.mol

Synonyms:582-65-0;4,4,4-trifluoro-1-(4-fluorophenyl)butane-1,3-dione;3-(4-fluorobenzoyl)-1,1,1-trifluoroacetone;4,4,4-trifluoro-1-(4-fluorophenyl)-1,3-butanedione;1,3-Butanedione, 4,4,4-trifluoro-1-(4-fluorophenyl)-;4,4,4-Trifluoro-1-(4-fluoro-phenyl)-butane-1,3-dione;SCHEMBL711849;DTXSID60377947;BBL010145;MFCD03419766;STK298731;AKOS000210695;CS-W012914;FT-0679215;C78326;EN300-143651;2T-0837;A831810;1-(4-Fluorophenyl)-4,4,4-trifluoro-1,3-butanedione;1-(4-fluoro-phenyl)-4,4,4-trifluoro-butane-1,3-dione;4,4,4-trifluoro-1-[4-(fluoro)phenyl]-butane-1,3-dione

Suppliers and Price of 4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione
10g
$ 160.00

TRC
4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione
5g
$ 125.00

Matrix Scientific
4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione
500mg
$ 189.00

Crysdot
4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione 95+%
10g
$ 361.00

Crysdot
4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione 95+%
25g
$ 722.00

Chemenu
4,4,4-Trifluoro-1-(4-fluorophenyl)-1,3-butanedione 95%+
1g
$ 59.00

Chemenu
4,4,4-Trifluoro-1-(4-fluorophenyl)-1,3-butanedione 95%+
5g
$ 206.00

Atlantic Research Chemicals
4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione 95%
10gm:
$ 318.11

American Custom Chemicals Corporation
4,4,4-TRIFLUORO-1-(4-FLUOROPHENYL)BUTANE-1,3-DIONE 95.00%
1G
$ 727.65

American Custom Chemicals Corporation
4,4,4-TRIFLUORO-1-(4-FLUOROPHENYL)BUTANE-1,3-DIONE 95.00%
10G
$ 1559.25

Total 21 raw suppliers

Chemical Property of 4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione

Chemical Property:

Vapor Pressure:0.0149mmHg at 25°C
Melting Point:40-42°C
Refractive Index:1.448
Boiling Point:257°C at 760 mmHg
PKA:5.61±0.25(Predicted)
Flash Point:98°C
PSA：34.14000
Density:1.363g/cm³
LogP:2.52990
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:234.03039208
Heavy Atom Count:16
Complexity:277

Purity/Quality:

95% ^*data from raw suppliers

4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)CC(=O)C(F)(F)F)F
Uses 4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dioneis an intermediate in the synthesis of Mavacoxib (M197900) which is a long-acting COX-2 Inhibitor and is developed as a veterinary drug used to treat pain and inflammation with degenerative joint disease for dogs.

Technology Process of 4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione

There total 4 articles about 4,4,4-Trifluoro-1-(4-fluorophenyl)butane-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%