4-bromo-N,N-dimethyl-3-(trifluoromethyl)aniline

Base Information

Chemical Name:4-bromo-N,N-dimethyl-3-(trifluoromethyl)aniline
CAS No.:51332-24-2
Molecular Formula:C9H9BrF3N
Molecular Weight:268.078
Hs Code.:2921430090
European Community (EC) Number:684-525-6
DSSTox Substance ID:DTXSID90350824
Wikidata:Q82126924
Mol file:51332-24-2.mol

Synonyms:4-bromo-N,N-dimethyl-3-(trifluoromethyl)aniline;51332-24-2;SCHEMBL1536726;DTXSID90350824;DBSFECXQLNDZAX-UHFFFAOYSA-N;MFCD00219439;AKOS015835301;DS-0541;CS-0186968;FT-0648029;4-Bromo-N,N-dimethyl-3-(trifluoromethyl);aniline;[4-bromo-3-(trifluoromethyl)-phenyl]-dimethyl-amine;Benzenamine, 4-bromo-N,N-dimethyl-3-(trifluoromethyl)-;InChI=1/C9H9BrF3N/c1-14(2)6-3-4-8(10)7(5-6)9(11,12)13/h3-5H,1-2H

Suppliers and Price of 4-bromo-N,N-dimethyl-3-(trifluoromethyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemcia Scientific
(4-Bromo-3-trifluoromethyl-phenyl)-dimethyl-amine 95%
5 G
$ 615.00

American Custom Chemicals Corporation
[4-BROMO-3-(TRIFLUOROMETHYL)PHENYL]DIMETHYLAMINE 95.00%
5MG
$ 496.08

Alichem
4-Bromo-N,N-dimethyl-3-(trifluoromethyl)aniline
5g
$ 966.28

Alichem
4-Bromo-N,N-dimethyl-3-(trifluoromethyl)aniline
1g
$ 322.42

AK Scientific
4-BROMO-N,N-DIMETHYL-3-(TRIFLUOROMETHYL)ANILINE
1g
$ 230.00

Abosyn
4-Bromo-N,N-dimethyl-3-(trifluoromethyl)aniline 95%-98%
1g
$ 165.00

Total 24 raw suppliers

Chemical Property of 4-bromo-N,N-dimethyl-3-(trifluoromethyl)aniline

Chemical Property:

Vapor Pressure:0.028mmHg at 25°C
Refractive Index:1.513
Boiling Point:245.9°C at 760 mmHg
Flash Point:102.5°C
PSA：3.24000
Density:1.543 g/mL at 25 °C(lit.)
LogP:3.53390
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:266.98705
Heavy Atom Count:14
Complexity:193

Purity/Quality:

97% ^*data from raw suppliers

(4-Bromo-3-trifluoromethyl-phenyl)-dimethyl-amine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 20/21/22-36/37/38
Safety Statements: 26-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=CC(=C(C=C1)Br)C(F)(F)F

Technology Process of 4-bromo-N,N-dimethyl-3-(trifluoromethyl)aniline

There total 3 articles about 4-bromo-N,N-dimethyl-3-(trifluoromethyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 393-36-2
4-bromo-3-(trifluoromethyl)aniline

: 74-88-4
methyl iodide

: 51332-24-2
5-dimethylamino-2-bromo-α,α,α-trifluorotoluene

Guidance literature:: With 2,6-dimethylpyridine; 2,6-di-tert-butyl-pyridine; In N,N-dimethyl-formamide; at 50 ℃; for 20h;
DOI:10.1246/cl.2007.24

Reference yield: 48.0%

: 3-(trifluoromethyl)-N,N-dimethylaniline N-oxide

: 51332-24-2
5-dimethylamino-2-bromo-α,α,α-trifluorotoluene

Guidance literature:: 3-(trifluoromethyl)-N,N-dimethylaniline N-oxide; With sulfurous dibromide; In tetrahydrofuran; at -78 ℃; for 4h; Inert atmosphere;

With triethylamine; In tetrahydrofuran; at -78 - 23 ℃; for 0.75h; regioselective reaction; Inert atmosphere;
DOI:10.1021/acs.joc.8b01590