1-[2-[[2-[[2-[[2-[(2-amino-3-hydroxypropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide

Base Information

Chemical Name:1-[2-[[2-[[2-[[2-[(2-amino-3-hydroxypropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide
CAS No.:51776-33-1
Molecular Formula:C33H53N11O9
Molecular Weight:747.852
Hs Code.:
European Community (EC) Number:637-109-3
DSSTox Substance ID:DTXSID90401002
Mol file:51776-33-1.mol

1-[2-[[2-[[2-[[2-[(2-amino-3-hydroxypropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide

Synonyms:51776-33-1;1-[2-[[2-[[2-[[2-[(2-amino-3-hydroxypropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide;H-Ser-tyr-gly-leu-arg-pro-gly-nh2;SCHEMBL11884805;DTXSID90401002;FT-0689008

Suppliers and Price of 1-[2-[[2-[[2-[[2-[(2-amino-3-hydroxypropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Biorbyt Ltd
LHRH (4-10) > 95%
10 mg
$ 708.90

Biorbyt Ltd
LHRH (4-10) > 95%
5 mg
$ 552.50

Biorbyt Ltd
LHRH (4-10) > 95%
1 mg
$ 287.30

American Custom Chemicals Corporation
LUTEINIZING HORMONE RELEASING HORMONE FRAGMENT 4-10 95.00%
5MG
$ 1008.14

Total 12 raw suppliers

Chemical Property of 1-[2-[[2-[[2-[[2-[(2-amino-3-hydroxypropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide

Chemical Property:

PKA:9.82±0.15(Predicted)
PSA：337.28000
Density:1.48±0.1 g/cm3(Predicted)
LogP:0.21070
Storage Temp.:−20°C
XLogP3:-3.1
Hydrogen Bond Donor Count:11
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:21
Exact Mass:747.40277231
Heavy Atom Count:53
Complexity:1300

Purity/Quality:

99%, ^*data from raw suppliers

LHRH (4-10) > 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 60
Safety Statements: 53-22-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)NC(CCCN=C(N)N)C(=O)N1CCCC1C(=O)NCC(=O)N)NC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)NC(=O)C(CO)N

Technology Process of 1-[2-[[2-[[2-[[2-[(2-amino-3-hydroxypropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide

There total 16 articles about 1-[2-[[2-[[2-[[2-[(2-amino-3-hydroxypropanoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2666-93-5
(S)-Leu-OMe

: 51776-33-1
luteinizing hormone-releasing hormone (4-10)

Guidance literature:: Multi-step reaction with 7 steps

2: Hydrogen bromide / acetic acid

4: NH₂NH₂

5: HNO₂

7: H₂ / catalytic hydrog.

With hydrogen bromide; hydrogen; cis-nitrous acid; hydrazine; In acetic acid;
DOI:10.1007/BF00714941

Reference yield:

: 17331-93-0
N-benzyloxycarbonylglycyl-L-leucine methyl ester

: 51776-33-1
luteinizing hormone-releasing hormone (4-10)

Guidance literature:: Multi-step reaction with 6 steps

1: Hydrogen bromide / acetic acid

3: NH₂NH₂

4: HNO₂

6: H₂ / catalytic hydrog.

With hydrogen bromide; hydrogen; cis-nitrous acid; hydrazine; In acetic acid;
DOI:10.1007/BF00714941

Reference yield:

: 1234-35-1
Z-Arg-OH

: 51776-33-1
luteinizing hormone-releasing hormone (4-10)

Guidance literature:: Multi-step reaction with 4 steps

2: hydrogen bromide / acetic acid

4: H₂ / catalytic hydrog.

With hydrogen bromide; hydrogen; In acetic acid;
DOI:10.1007/BF00714941