Methylzinc chloride

Base Information

Chemical Name:Methylzinc chloride
CAS No.:5158-46-3
Molecular Formula:CH3ClZn
Molecular Weight:115.878
Hs Code.:2931900090
European Community (EC) Number:628-657-4
Mol file:5158-46-3.mol

Synonyms:methylzinc chloride;5158-46-3;Methylzinc chloride, 1.0 M in THF;MFCD00192334

Suppliers and Price of Methylzinc chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Chloro(Methyl)Zinc
250mg
$ 45.00

Sigma-Aldrich
Methylzinc chloride solution 2.0 M in THF
50ml
$ 516.00

American Custom Chemicals Corporation
CHLORO(METHYL)ZINC 95.00%
10G
$ 1382.48

American Custom Chemicals Corporation
CHLORO(METHYL)ZINC 95.00%
5G
$ 955.42

American Custom Chemicals Corporation
CHLORO(METHYL)ZINC 95.00%
1G
$ 646.25

Total 10 raw suppliers

Chemical Property of Methylzinc chloride

Chemical Property:

Boiling Point:67 °C
Flash Point:−18 °F
PSA：0.00000
Density:1.033 g/mL at 25 °C
LogP:1.27080
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:113.921470
Heavy Atom Count:3
Complexity:4.8

Purity/Quality:

98%,99%, ^*data from raw suppliers

Chloro(Methyl)Zinc ^*data from reagent suppliers

Safty Information:

Pictogram(s): F,Xi
Hazard Codes:F,Xi,C
Statements: 11-19-36/37/38-40-37-34
Safety Statements: 16-26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:[CH3-].Cl[Zn+]
Uses Methylzinc chloride can be used in: Ni-catalyzed one-pot Negishi coupling with amino-heteroaryl chlorides.Cross-coupling with aryl fluorides in the presence of a nickel catalyst.

Technology Process of Methylzinc chloride

There total 3 articles about Methylzinc chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 42536-20-9,42536-21-0,84107-83-5
WCl(CO)2(NO)(P(C₆H₅)3)2

: 544-97-8
dimethyl zinc(II)

: 108417-91-0
W(CH₃)(CO)2(NO)(P(C₆H₅)3)2

: 5158-46-3
methylzinc chloride

Guidance literature:: In tetrahydrofuran; (Ar); (CH3)2Zn (6.1 mmol) added to soln. of W compd. (0.51 mmol) at -78°C; soln. allowed to warm to ambient temp. and stirred for 10 h; soln. evapd. (vac.); CH2Cl2 added; filtration (Celite); EtOH added to the filtrate; ppt. filtered and washed sequentially (EtOH, diethyl ether,petroleum ether) to give microcrystals; elem. anal.;

Reference yield: 51.0%

: chlorodimethyloxobis(dimethylphenylphosphine)rhenium(V)

: 544-97-8
dimethyl zinc(II)

: trimethyloxo(dimethylphenylphosphine)rhenium(V)

: 672-66-2
Dimethyl(phenyl)phosphine

: 5158-46-3
methylzinc chloride

Guidance literature:: In toluene; N2 or Ar atmosphere of vac.; 0°C; removal of solvent (0°C, vac.), extn. (pentane), removal of pentane (vac.);
DOI:10.1016/S0277-5387(00)86452-9

Reference yield: 47.0%

: chlorodimethyloxobis(trimethylphosphine)rhenium(V)

: 544-97-8
dimethyl zinc(II)

: trimethyloxo(trimethylphosphine)rhenium(V)

: 594-09-2
trimethylphosphane

: 5158-46-3
methylzinc chloride

Guidance literature:: In toluene; N2 or Ar atmosphere of vac.; 0°C; removal of solvent (0°C, vac.), extn. (pentane), removal of pentane (vac.);
DOI:10.1016/S0277-5387(00)86452-9