Butyl Methanethiosulfonate

Base Information

• Chemical Name: Butyl Methanethiosulfonate
• CAS No.: 52017-46-6
• Molecular Formula: C5H12O2S2
• Molecular Weight: 168.28
• Hs Code.: 2930909090
• Mol file: 52017-46-6.mol

Synonyms:Methanthiosulfonsaeure-S-butylester;Methanesulfonothioic acid;Methylthiosulfonsaeure;Methanthiosulfonsaeure;Methanethiosulfonate;Methanethiosulfonicacid;methanethiosulfonic acid S-butyl ester;hydroxy-methyl-oxo-sulfanylidene;

Chemical Property of Butyl Methanethiosulfonate

Chemical Property:

• Vapor Pressure: 0.00263mmHg at 25°C
• Refractive Index: 1.487
• Boiling Point: 68-72°C/0.5 mm
• Flash Point: 132.7°C
• PSA: 67.82000
• Density: 1.152g/cm³
• LogP: 2.56010
• Storage Temp.: Refrigerator

Purity/Quality:

98% ^*data from raw suppliers

ButylMethanethiosulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Butyl methanethiosulfonate reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease.

Technology Process of Butyl Methanethiosulfonate

There total 2 articles about Butyl Methanethiosulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

dibutyl disulfide (629-45-8) + sodium methansulfinate (20277-69-4) → S-butyl methanethiosulfonate (52017-46-6)

Guidance literature:

With iodine; In dichloromethane; for 24h;

DOI:10.1002/anie.201406717

Reference yield:

1-bromo-butane (109-65-9) → S-butyl methanethiosulfonate (52017-46-6)

Guidance literature:

Reference yield: 77.0%

S-butyl methanethiosulfonate (52017-46-6) + tert-butylisonitrile (119072-55-8,7188-38-7) + aniline (62-53-3) → S-butyl-N-tert-butyl-N’-phenylisothiourea

Guidance literature:

With copper(l) iodide; In 2-methyltetrahydrofuran; at 75 ℃; for 20h; Molecular sieve;

DOI:10.1002/anie.201406717

upstream raw materials:

1-bromo-butane

dibutyl disulfide

sodium methansulfinate

Downstream raw materials:

2-(isopropyldisulfanyl)pyridine

2-(methyldisulfanyl)pyridine

2-(ethyldisulfaneyl)pyridine

2-pyridyl 1-methylpropyl disulfide

Refernces