N,N-DIMETHYL-N'-(2-(METHYLSULFONYL)PYRIMIDIN-5-YL)FORMIMIDAMIDE

Base Information

• Chemical Name: N,N-DIMETHYL-N'-(2-(METHYLSULFONYL)PYRIMIDIN-5-YL)FORMIMIDAMIDE
• CAS No.: 56622-05-0
• Molecular Formula: C₈H₁₂N₄O₂S
• Molecular Weight: 228.275
• Mol file: 56622-05-0.mol

Synonyms:N,N-DIMETHYL-N'-(2-(METHYLSULFONYL)PYRIMIDIN-5-YL)FORMIMIDAMIDE

Chemical Property of N,N-DIMETHYL-N'-(2-(METHYLSULFONYL)PYRIMIDIN-5-YL)FORMIMIDAMIDE

Chemical Property:

• PSA: 83.90000
• LogP: 1.18230

Purity/Quality:

99% ^*data from raw suppliers

N,N-DIMETHYL-N'-(2-(METHYLSULFONYL)PYRIMIDIN-5-YL)FORMIMIDAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-DIMETHYL-N'-(2-(METHYLSULFONYL)PYRIMIDIN-5-YL)FORMIMIDAMIDE

There total 3 articles about N,N-DIMETHYL-N'-(2-(METHYLSULFONYL)PYRIMIDIN-5-YL)FORMIMIDAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethyl-N-[2-(dimethylaminomethylene)amino-3-dimethylamino]prop-2-enylideneammonium perchlorate → N'-(2-methanesulfonyl-pyrimidin-5-yl)-N,N-dimethyl-formamidine (56622-05-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / NaOMe / ethanol; methanol / 3 h / Heating

2: aq. NaClO₄; aq. NaHCO₃ / 1 h

With sodium perchlorate; sodium methylate; sodium hydrogencarbonate; In methanol; ethanol;

DOI:10.1248/cpb.48.1504

Reference yield:

2-methylthio-5-dimethylaminomethyleneaminopyrimidine (52767-93-8) → N'-(2-methanesulfonyl-pyrimidin-5-yl)-N,N-dimethyl-formamidine (56622-05-0)

Guidance literature:

With sodium perchlorate; sodium hydrogencarbonate; for 1h;

DOI:10.1248/cpb.48.1504

Reference yield:

→ N'-(2-methanesulfonyl-pyrimidin-5-yl)-N,N-dimethyl-formamidine (56622-05-0)

Guidance literature:

Pyrimidin IIId, NaClO;

upstream raw materials:

2-methylthio-5-dimethylaminomethyleneaminopyrimidine

Refernces