3-(4-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER

Base Information

Chemical Name:3-(4-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER
CAS No.:52116-83-3
Molecular Formula:C₁₁H₉NO₂
Molecular Weight:187.198
Hs Code.:2926909090
Mol file:52116-83-3.mol

Synonyms:3-(4-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER;METHYL 3-(4-CYANOPHENYL)ACRYLATE;Methyl 4-cyanocinnamate

Suppliers and Price of 3-(4-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl4-Cyanocinnamate
250mg
$ 70.00

Medical Isotopes, Inc.
Methyl4-Cyanocinnamate
5 g
$ 1225.00

Crysdot
Methyl3-(4-cyanophenyl)acrylate 97%
1g
$ 318.00

Alichem
Methyl3-(4-cyanophenyl)acrylate
1g
$ 400.00

Alfa Aesar
Methyl 4-cyanocinnamate, 97%
1g
$ 191.00

Alfa Aesar
Methyl 4-cyanocinnamate, 97%
250mg
$ 53.80

Total 13 raw suppliers

Chemical Property of 3-(4-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:112-125℃
Refractive Index:1.548
Boiling Point:339.939°C at 760 mmHg
Flash Point:161.152°C
PSA：50.09000
Density:1.153g/cm³
LogP:1.74448

Purity/Quality:

99%, ^*data from raw suppliers

Methyl4-Cyanocinnamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Methyl 4-Cyanocinnamate is a reagent in the synthesis and evaluation of analogous diisopropylpyridine acetamides as potent antagonists of Kv1.5 potassium channel.

Technology Process of 3-(4-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER

There total 10 articles about 3-(4-CYANO-PHENYL)-ACRYLIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 623-00-7
4-bromobenzenecarbonitrile

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 52116-83-3,67472-79-1,71348-23-7
methyl 3‐(4‐cyanophenyl)acrylate

Guidance literature:: With potassium phosphate tribasic trihydrate; In 1-methyl-pyrrolidin-2-one; at 140 ℃; for 0.5h;
DOI:10.1016/S1872-2067(15)60952-4

Reference yield: 95.0%

: 3058-39-7
4-iodobenzonitrile

: 292638-85-8,9003-21-8,96-33-3
acrylic acid methyl ester

: 52116-83-3,67472-79-1,71348-23-7
methyl 3‐(4‐cyanophenyl)acrylate

Guidance literature:: With sodium acetate; In 1,2-dimethoxyethane; water; at 90 ℃; for 5h; regioselective reaction; Sealed tube;
DOI:10.1021/jacs.8b03505