2,3-Quinolinedimethanol

Base Information

Chemical Name:2,3-Quinolinedimethanol
CAS No.:57032-14-1
Molecular Formula:C11H11NO2
Molecular Weight:189.214
Hs Code.:
European Community (EC) Number:827-756-1
DSSTox Substance ID:DTXSID40458687
Wikidata:Q82282162
Mol file:57032-14-1.mol

Synonyms:2,3-Quinolinedimethanol;57032-14-1;QUINOLINE-2,3-DIYLDIMETHANOL;[2-(hydroxymethyl)quinolin-3-yl]methanol;[3-(HYDROXYMETHYL)QUINOLIN-2-YL]METHANOL;SCHEMBL7927501;DTXSID40458687;AKOS006293692;AB21169;AC-13266;FT-0691400;EN300-6474520

Suppliers and Price of 2,3-Quinolinedimethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,3-QUINOLINEDIMETHANOL 95.00%
5MG
$ 500.78

AK Scientific
2,3-Quinolinedimethanol
2.5g
$ 2534.00

AK Scientific
2,3-Quinolinedimethanol
250mg
$ 738.00

AK Scientific
2,3-Quinolinedimethanol
100mg
$ 553.00

Total 5 raw suppliers

Chemical Property of 2,3-Quinolinedimethanol

Chemical Property:

Vapor Pressure:9.96E-07mmHg at 25°C
Refractive Index:1.688
Boiling Point:388.4°C at 760 mmHg
Flash Point:188.7°C
PSA：53.35000
Density:1.31g/cm³
LogP:1.21940
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:189.078978594
Heavy Atom Count:14
Complexity:186

Purity/Quality:

98%min ^*data from raw suppliers

2,3-QUINOLINEDIMETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(C(=N2)CO)CO
Uses 2,3-Quinolinedimethanol is a reactant used in the synthesis of camptothecin (C175150), an ntitumor alkaloid which binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent

Technology Process of 2,3-Quinolinedimethanol

There total 9 articles about 2,3-Quinolinedimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 778593-74-1
acetic acid {2-(acetoxymethyl)quinolin-3-yl}methyl ester

: 57032-14-1
2-hydroxymethyl-quinolin-3-yl-methanol

Guidance literature:: With potassium carbonate; In methanol; water; at 20 ℃; for 0.5h;
DOI:10.1081/SCC-200028560

Reference yield:

: 1088402-56-5
(3-formylquinolin-2-yl)methyl acetate

: 57032-14-1
2-hydroxymethyl-quinolin-3-yl-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: methanol; potassium borohydride / 0.17 h / -20 °C

2: potassium carbonate / methanol / 0.17 h / -20 - 20 °C

With methanol; potassium borohydride; potassium carbonate; In methanol;
DOI:10.1002/asia.201403190