Methyl 5-(4-aminophenyl)furan-2-carboxylate

Base Information

Chemical Name:Methyl 5-(4-aminophenyl)furan-2-carboxylate
CAS No.:52939-06-7
Molecular Formula:C12H11NO3
Molecular Weight:217.224
Hs Code.:2932190090
European Community (EC) Number:622-192-0
DSSTox Substance ID:DTXSID20461952
Wikidata:Q82286412
Mol file:52939-06-7.mol

Synonyms:52939-06-7;Methyl 5-(4-aminophenyl)furan-2-carboxylate;5-(4-Aminophenyl)furan-2-carboxylic acid methyl ester;Methyl 5-(4-aminophenyl)-2-furoate;SCHEMBL1143497;DTXSID20461952;JOIQXOMSFVFDQY-UHFFFAOYSA-N;MFCD06797396;AKOS015894351;SB61206;AS-47628;CS-0204429;EN300-734290;F14715;A870868;Methyl 5-(4-aminophenyl)furan-2-carboxylate, 97%;5-(4-AMINOPHENYL)FURAN-2-CARBOXYLICACIDMETHYLESTER

Suppliers and Price of Methyl 5-(4-aminophenyl)furan-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(4-Aminophenyl)furan-2-carboxylicacidmethylester
1g
$ 175.00

Sigma-Aldrich
Methyl 5-(4-aminophenyl)furan-2-carboxylate 97%
1g
$ 99.90

Sigma-Aldrich
Methyl 5-(4-aminophenyl)furan-2-carboxylate 97%
5g
$ 388.00

Chemenu
Methyl 5-(4-aminophenyl)furan-2-carboxylate 95%
5g
$ 333.00

American Custom Chemicals Corporation
5-(4-AMINOPHENYL)FURAN-2-CARBOXYLIC ACID METHYL ESTER 95.00%
5G
$ 1140.59

American Custom Chemicals Corporation
5-(4-AMINOPHENYL)FURAN-2-CARBOXYLIC ACID METHYL ESTER 95.00%
1G
$ 697.69

Alichem
Methyl 5-(4-aminophenyl)furan-2-carboxylate
5g
$ 296.64

AK Scientific
5-(4-Aminophenyl)furan-2-carboxylicacidmethylester
1g
$ 157.00

Total 17 raw suppliers

Chemical Property of Methyl 5-(4-aminophenyl)furan-2-carboxylate

Chemical Property:

Vapor Pressure:3.98E-06mmHg at 25°C
Melting Point:122-126 °C(lit.)
Refractive Index:1.58
Boiling Point:384.8°Cat760mmHg
Flash Point:186.5°C
PSA：65.46000
Density:1.222g/cm³
LogP:2.89660
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:217.07389321
Heavy Atom Count:16
Complexity:249

Purity/Quality:

97% ^*data from raw suppliers

5-(4-Aminophenyl)furan-2-carboxylicacidmethylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=C(O1)C2=CC=C(C=C2)N

Technology Process of Methyl 5-(4-aminophenyl)furan-2-carboxylate

There total 4 articles about Methyl 5-(4-aminophenyl)furan-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 52939-00-1
5-(4-nitrophenyl)furan-2-carboxylic acid methyl ester

: 52939-06-7
5-(4-aminophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 2h; under 2280 Torr;
DOI:10.1021/jm0492305

Reference yield:

: 2527-99-3
methyl 5-bromo-2-furoate

: 52939-06-7
5-(4-aminophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / Pd(PPh₃)4; aq. Na₂CO₃ / toluene; methanol / 6 h / Heating

2: 97 percent / H₂ / Pd/C / methanol / 2 h / 20 °C / 2280 Torr

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen; sodium carbonate; palladium on activated charcoal; In methanol; toluene; 1: Suzuki reaction;
DOI:10.1021/jm0492305

Reference yield:

: 24067-17-2
4-nitrophenylboronic acid

: 52939-06-7
5-(4-aminophenyl)furan-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / Pd(PPh₃)4; aq. Na₂CO₃ / toluene; methanol / 6 h / Heating

2: 97 percent / H₂ / Pd/C / methanol / 2 h / 20 °C / 2280 Torr

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; hydrogen; sodium carbonate; palladium on activated charcoal; In methanol; toluene; 1: Suzuki reaction;
DOI:10.1021/jm0492305