(6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-ACETIC ACID

Base Information

• Chemical Name: (6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-ACETIC ACID
• CAS No.: 57351-00-5
• Molecular Formula: C13H16O3
• Molecular Weight: 220.268
• Hs Code.: 2918990090
• Mol file: 57351-00-5.mol

Synonyms:6-Methoxy-1,2,3,4-tetrahydro-2-naphthylacetic acid;1,2,3,4-tetrahydro-6-methoxynaphthalene-2-acetic acid;<6-Methoxy-1,2,3,4-tetrahydro-<2>naphthyl>-essigsaeure;

Chemical Property of (6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-ACETIC ACID

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.542
• Boiling Point: 404.002°C at 760 mmHg
• PKA: 4?+-.0.10(Predicted)
• Flash Point: 156.098°C
• PSA: 46.53000
• Density: 1.144g/cm³
• LogP: 2.27480

Purity/Quality:

98%Min ^*data from raw suppliers

(6-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-ACETIC ACID

There total 6 articles about (6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

<6-Methoxy-1,2,3,4-tetrahydro-<2>naphthyl>-essigsaeure-aethylester (108975-09-3) → 1,2,3,4-tetrahydro-6-methoxynaphthalene-2-acetic acid (57351-00-5)

Guidance literature:

(6-methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-acetic acid ethyl ester; With methanol; lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 2h;

With hydrogenchloride;

Reference yield:

6-methoxy-3,4-dihydro-1(2H)-naphthalenone (1078-19-9) → 1,2,3,4-tetrahydro-6-methoxynaphthalene-2-acetic acid (57351-00-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 85 percent / NaH

2: 1.) sodium derivative / 2.) DME

3: 70 percent / 6N hydrochloric acid / acetic acid / 8 h

4: 1.) NaBH₄, NaOH, 2.) hydrogen / 2.) 10percent Pd on carbon / 1. water, 2.) acetic acid

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; hydrogen; sodium; sodium hydride; palladium on activated charcoal; In acetic acid;

Reference yield:

ethyl 6-methoxy-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate (16425-80-2) → 1,2,3,4-tetrahydro-6-methoxynaphthalene-2-acetic acid (57351-00-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) sodium derivative / 2.) DME

2: 70 percent / 6N hydrochloric acid / acetic acid / 8 h

3: 1.) NaBH₄, NaOH, 2.) hydrogen / 2.) 10percent Pd on carbon / 1. water, 2.) acetic acid

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; hydrogen; sodium; palladium on activated charcoal; In acetic acid;

upstream raw materials:

6-methoxy-1-oxo-1,2,3,4-tetrahydronaphthalene-2-acetic acid

2-(6-methoxy-1-oxo-3,4-dihydronaphthalen-2(1H)-ylidene)acetic acid

ethyl 6-methoxy-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate

6-methoxy-2-ethoxycarbonyl-2-(ethoxycarbonylmethyl)-1-tetralone

Downstream raw materials:

2-<6-Benzyloxy-1,2,3,4-tetrahydro-naphthyl-(2)>-ethanol

2-<6-Benzyloxy-1,2,3,4-tetrahydro-naphthyl-(2)>-ethyl-p-toluolsulfonat

6-Benzyloxy-1,2,3,4-tetrahydronaphthylacetic acid

(2RS,5SR,10SR)-hinesol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 57351-00-5 (6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YL)-ACETIC ACID

Send

Send

Metric Ton KG G Pound L ML

Send

Send