(2-Hydroxyphenyl)phosphonic acid

Base Information

Chemical Name:(2-Hydroxyphenyl)phosphonic acid
CAS No.:53104-46-4
Molecular Formula:C6H7O4P
Molecular Weight:174.09
Hs Code.:2931900090
DSSTox Substance ID:DTXSID30391675
Wikidata:Q82189312
Mol file:53104-46-4.mol

Synonyms:(2-hydroxyphenyl)phosphonic acid;53104-46-4;2-Hydroxyphenylphosphonic acid;phenol phosphonate;EC-000.1462;Oprea1_864287;SCHEMBL1227487;DTXSID30391675;MFCD00778041;STK373199;AKOS005446693;FT-0640130

Suppliers and Price of (2-Hydroxyphenyl)phosphonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(2-HYDROXYPHENYL)PHOSPHONIC ACID 95.00%
5MG
$ 497.85

AHH
(2-Hydroxyphenyl)phosphonicacid 98%
5g
$ 845.00

Total 5 raw suppliers

Chemical Property of (2-Hydroxyphenyl)phosphonic acid

Chemical Property:

Vapor Pressure:1.27E-07mmHg at 25°C
Melting Point:178-179 °C
Refractive Index:1.62
Boiling Point:414.7°C at 760 mmHg
PKA:1.93±0.10(Predicted)
Flash Point:204.6°C
PSA：87.57000
Density:1.6g/cm³
LogP:0.19520
XLogP3:0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:174.00819570
Heavy Atom Count:11
Complexity:175

Purity/Quality:

98% ^*data from raw suppliers

(2-HYDROXYPHENYL)PHOSPHONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)O)P(=O)(O)O

Technology Process of (2-Hydroxyphenyl)phosphonic acid

There total 7 articles about (2-Hydroxyphenyl)phosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 98057-61-5
di-t-butyl (2-hydroxyphenyl) phosphonate

: 53104-46-4
2-hydroxybenzenephosphonic acid

Guidance literature:: With trifluoroacetic acid; In benzene; for 24h; Ambient temperature;

Reference yield:

: 2510-86-3
O,O-diethyl O-phenyl phosphate

: 53104-46-4
2-hydroxybenzenephosphonic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / diisopropylamine, n-butyllithium / tetrahydrofuran / -78 °C

2: 1) chlorotrimethylsilane, sodium iodide 2) water / 1) acetonitrile a) 1h 40 deg C b) 1.5h room temperature 2) 2h room temperature

With n-butyllithium; chloro-trimethyl-silane; water; diisopropylamine; sodium iodide; In tetrahydrofuran;
DOI:10.1021/jo00195a029

Reference yield:

: 69646-14-6
(2-hydroxy-phenyl)-phosphonic acid diethyl ester

: 53104-46-4
2-hydroxybenzenephosphonic acid

Guidance literature:: With chloro-trimethyl-silane; water; sodium iodide; Yield given. Multistep reaction; 1) acetonitrile a) 1h 40 deg C b) 1.5h room temperature 2) 2h room temperature;
DOI:10.1021/jo00195a029