3,5-Dimethylbenzo[d]isoxazole

Base Information

Chemical Name:3,5-Dimethylbenzo[d]isoxazole
CAS No.:53155-26-3
Molecular Formula:C9H9NO
Molecular Weight:147.177
Hs Code.:
DSSTox Substance ID:DTXSID801306675
Nikkaji Number:J3.019.998G
Mol file:53155-26-3.mol

Synonyms:3,5-dimethylbenzo[d]isoxazole;53155-26-3;3,5-dimethyl-1,2-benzisoxazole;1,2-Benzisoxazole,3,5-dimethyl-;1,2-Benzisoxazole, 3,5-dimethyl-;SCHEMBL5985206;DTXSID801306675;AKOS006272030;FT-0695437

Suppliers and Price of 3,5-Dimethylbenzo[d]isoxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3,5-DIMETHYL-1,2-BENZISOXAZOLE 95.00%
5MG
$ 501.78

Total 3 raw suppliers

Chemical Property of 3,5-Dimethylbenzo[d]isoxazole

Chemical Property:

PSA：26.03000
LogP:2.44460
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:147.068413911
Heavy Atom Count:11
Complexity:149

Purity/Quality:

99% ^*data from raw suppliers

3,5-DIMETHYL-1,2-BENZISOXAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC2=C(C=C1)ON=C2C

Technology Process of 3,5-Dimethylbenzo[d]isoxazole

There total 7 articles about 3,5-Dimethylbenzo[d]isoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 25172-54-7,3973-90-8
1-(2-hydroxy-5-methylphenyl)ethan-1-one oxime

: 53155-26-3
3,5-dimethyl-1,2-benzisoxazole

Guidance literature:: With silica gel supported sodium carbonate; water; for 0.05h; Cooling; Microwave irradiation; neat (no solvent);

Reference yield: 91.0%

: 33598-02-6
2'-hydroxy-5'-methylacetophenone imine

: 53155-26-3
3,5-dimethyl-1,2-benzisoxazole

Guidance literature:: With N-chloro-succinimide; potassium carbonate; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1021/ol202844c

Reference yield:

: 1450-72-2
5-methyl-2-hydroxyacetophenone

: 53155-26-3
3,5-dimethyl-1,2-benzisoxazole

Guidance literature:: Multi-step reaction with 3 steps

1: 1) 40percent KOH 2) NH₂OH*HCl / 1) H₂O 2) 4h

2: Heating

3: 1 h / 125 °C / 0.1 Torr

With potassium hydroxide; hydroxylamine hydrochloride;