BOC-4-METHOXY-DL-PHENYLALANINE DICYCLOHEXYLAMMONIUM SALT

Base Information

• Chemical Name: BOC-4-METHOXY-DL-PHENYLALANINE DICYCLOHEXYLAMMONIUM SALT
• CAS No.: 53267-94-0
• Molecular Formula: C₁₂H₂₃N*C₁₅H₂₁NO₅
• Molecular Weight: 476.657
• Mol file: 53267-94-0.mol

Synonyms:BOC-O-METHYL-L-TYROSINE DCHA SALT;BOC-O-METHYL-L-TYROSINE DICYCLOHEXYLAMMONIUM SALT;BOC-P-METHOXY-DL-PHE-OH DCHA;BOC-P-METHOXY-PHE-OH DCHA;BOC-PHE(OME)-OH DCHA;BOC-TYR(ME)-OH DCHA;BOC-4-METHOXY-DL-PHENYLALANINE DICYCLOHEXYLAMMONIUM SALT;BOC-DL-TYR(ME)-OH DCHA

Chemical Property of BOC-4-METHOXY-DL-PHENYLALANINE DICYCLOHEXYLAMMONIUM SALT

Chemical Property:

• PSA: 96.89000
• LogP: 6.23880
• Storage Temp.: Store at 0°C

Purity/Quality:

98%min ^*data from raw suppliers

Boc-3-methoxy-L-tyrosine(dicyclohexylammonium) salt 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BOC-4-METHOXY-DL-PHENYLALANINE DICYCLOHEXYLAMMONIUM SALT

There total 2 articles about BOC-4-METHOXY-DL-PHENYLALANINE DICYCLOHEXYLAMMONIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-t-butyloxycarbonyl-L-tyrosine (3978-80-1,70642-86-3,142847-18-5) → N-(tert-Butyloxycarbonyl)-O-methyltyrosin-Dicyclohexylammonium-Salz (53267-94-0)

Guidance literature:

Multi-step reaction with 2 steps

1: triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran; diethyl ether / 12 h / 0 °C

2: 1.) NaOH / 1.) EtOH, H₂O, 0 deg C, 1 h; 2.) toluene

With sodium hydroxide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; diethyl ether;

Reference yield:

2-tert-Butoxycarbonylamino-3-(4-methoxy-phenyl)-propionic acid methyl ester (94790-24-6) + N-cyclohexyl-cyclohexanamine (101-83-7) → N-(tert-Butyloxycarbonyl)-O-methyltyrosin-Dicyclohexylammonium-Salz (53267-94-0)

Guidance literature:

With sodium hydroxide; Yield given. Multistep reaction; 1.) EtOH, H₂O, 0 deg C, 1 h; 2.) toluene;

upstream raw materials:

2-tert-Butoxycarbonylamino-3-(4-methoxy-phenyl)-propionic acid methyl ester

N-cyclohexyl-cyclohexanamine

N-t-butyloxycarbonyl-L-tyrosine

Refernces