3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-1-amine

Base Information

Chemical Name:3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-1-amine
CAS No.:5596-87-2
Molecular Formula:C12H18N2
Molecular Weight:190.288
Hs Code.:2933499090
European Community (EC) Number:830-271-8
DSSTox Substance ID:DTXSID50427960
Nikkaji Number:J1.157.435A
Wikidata:Q27455181
Mol file:5596-87-2.mol

Synonyms:3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-1-amine;5596-87-2;3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-amine;3-(3,4-dihydro-1H-isoquinolin-2-yl)propan-1-amine;C12H18N2;MFCD06446877;SCHEMBL2795026;DTXSID50427960;STK504345;AKOS000123486;LS-02628;CS-0453601;EN300-33580;A1-26328;Q27455181;3-[3,4-Dihydroisoquinoline-2(1H)-yl]propane-1-amine;F2187-2292;Z271005928;4X1

Suppliers and Price of 3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(3,4-Dihydroisoquinolin-2(1h)-yl)propan-1-amine
500mg
$ 235.00

TRC
3-(3,4-Dihydroisoquinolin-2(1h)-yl)propan-1-amine
100mg
$ 75.00

SynQuest Laboratories
3-(3,4-Dihydroisoquinolin-2(1H)-yl)propan-1-amine 95%
1 g
$ 888.00

Matrix Scientific
3-(3,4-Dihydroisoquinolin-2(1H)-yl)propan-1-amine
500mg
$ 189.00

Crysdot
3-(3,4-Dihydroisoquinolin-2(1H)-yl)propan-1-amine 95+%
1g
$ 377.00

Chemenu
3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-1-amine 95%
1g
$ 356.00

Biosynth Carbosynth
3-(3,4-Dihydroisoquinolin-2(1H)-yl)propan-1-amine
500 mg
$ 150.00

Biosynth Carbosynth
3-(3,4-Dihydroisoquinolin-2(1H)-yl)propan-1-amine
2 g
$ 434.00

Biosynth Carbosynth
3-(3,4-Dihydroisoquinolin-2(1H)-yl)propan-1-amine
1 g
$ 255.00

Biosynth Carbosynth
3-(3,4-Dihydroisoquinolin-2(1H)-yl)propan-1-amine
250 mg
$ 85.00

Total 11 raw suppliers

Chemical Property of 3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-1-amine

Chemical Property:

Boiling Point:311.2±30.0 °C(Predicted)
PKA:10.06±0.10(Predicted)
PSA：29.26000
Density:1.028±0.06 g/cm3(Predicted)
LogP:2.03170
Storage Temp.:2-8°C
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:190.146998583
Heavy Atom Count:14
Complexity:170

Purity/Quality:

98%min ^*data from raw suppliers

3-(3,4-Dihydroisoquinolin-2(1h)-yl)propan-1-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CC2=CC=CC=C21)CCCN

Technology Process of 3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-1-amine

There total 7 articles about 3-(3,4-dihydroisoquinolin-2(1H)-yl)propan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 198895-33-9
2-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-2,3-dihydro-1H-isoindole-1,3-dione

: 5596-87-2
3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-amine

Guidance literature:: 2-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-2,3-dihydro-1H-isoindole-1,3-dione; With hydrazine hydrate; In ethanol; at 85 ℃; for 4h;

With hydrogenchloride; In ethanol; at 100 ℃; for 1h;

Reference yield:

: 91-21-4
1,2,3,4-tetrahydroisoquinoline

: 5460-29-7
2-(3-bromopropyl)isoindole-1,3-dione

: 5596-87-2
3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-amine

Guidance literature:: 1,2,3,4-tetrahydroisoquinoline; 2-(3-bromopropyl)isoindole-1,3-dione; With potassium carbonate; In acetonitrile; for 12h; Reflux;

With methylamine; sodium hydroxide; at 20 ℃; for 2h;
DOI:10.3390/molecules25173868

Reference yield:

: 91-21-4
1,2,3,4-tetrahydroisoquinoline

: 5596-87-2
3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-amine

Guidance literature:: Multi-step reaction with 2 steps

1: xylene / 24 h / 120 - 130 °C

2: hydrazine hydrate / ethanol / 1 h / Heating

With hydrazine hydrate; In ethanol; xylene;
DOI:10.1021/jm981101z