H-PRO-NHET HCL

Base Information

• Chemical Name: H-PRO-NHET HCL
• CAS No.: 58107-62-3
• Molecular Formula: C7H15ClN2O
• Molecular Weight: 178.662
• Hs Code.: 2933998090
• Mol file: 58107-62-3.mol

Synonyms:L-PROLINE ETHYLAMIDE HYDROCHLORIDE;H-PRO-NHET HCL;PROLINE-NHET HCL

Chemical Property of H-PRO-NHET HCL

Chemical Property:

• Boiling Point: 343.6°C at 760 mmHg
• PSA: 41.13000
• LogP: 1.39620
• Storage Temp.: -15°C
• Solubility.: Methanol (Slightly), Water (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

L-Proline ethylamide hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of H-PRO-NHET HCL

There total 3 articles about H-PRO-NHET HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.1%

ethylamine (75-04-7,85404-22-4) + L-proline (147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7) → L-proline ethylamide hydrochloride (58107-62-3,59179-36-1)

Guidance literature:

L-proline; With pyridine; dimethylsilicon dichloride; at 0 ℃; for 2h; Inert atmosphere;

ethylamine; at 0 - 20 ℃; for 1h; Inert atmosphere;

With hydrogenchloride; In water; Temperature;

DOI:10.1007/s10593-014-1474-7

Reference yield:

L-proline + ethylamine (75-04-7,85404-22-4) → L-proline ethylamide hydrochloride (58107-62-3,59179-36-1)

Guidance literature:

L-proline; ethylamine; at 20 ℃; for 1h; Inert atmosphere;

With hydrogenchloride; In water; Inert atmosphere;

DOI:10.1007/s10593-014-1474-7

Reference yield:

dimethylsilicon dichloride (75-78-5,30107-43-8) + L-proline (147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7) → L-proline ethylamide hydrochloride (58107-62-3,59179-36-1)

Guidance literature:

With pyridine; at 0 ℃; for 2h; Temperature; Inert atmosphere;

DOI:10.1007/s10593-014-1474-7

upstream raw materials:

dimethylsilicon dichloride

L-proline

ethylamine

Downstream raw materials:

Boc-Arg(Mtr)-Pro-NHEt