2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)acetic acid

Base Information

Chemical Name:2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)acetic acid
CAS No.:58237-94-8
Molecular Formula:C15H18N2O4
Molecular Weight:290.31
Hs Code.:2933990090
European Community (EC) Number:672-483-1
DSSTox Substance ID:DTXSID40373548
Mol file:58237-94-8.mol

Synonyms:58237-94-8;N-Boc-(3-indole)glycine;n-boc-2-(indole-3-yl)-dl-glycine;2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)acetic acid;2-(1H-indol-3-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetic Acid;[(tert-butoxycarbonyl)amino](1H-indol-3-yl)acetic acid;2-(tert-butoxycarbonylamino)-2-(1h-indol-3-yl)acetic acid;[(tert-Butoxycarbonyl)amino]-(1H-indol-3-yl)acetic acid;SCHEMBL11636711;DTXSID40373548;SORQKPVCWGOPQX-UHFFFAOYSA-N;MFCD03426367;AKOS022172795;N-Boc-(3-indole)glycine, AldrichCPR;AB33332;AS-37109;CS-0171871;FT-0652620;EN300-726372;alpha-(N-t-Butoxycarbonylamino)indole-3-acetic acid;Q-102924;F2147-1206;1H-ndole-3-cetic acid, -[(1,1-imethylethoxy)arbonyl]mino]-;2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)aceticacid;(R)-TERT-BUTOXYCARBONYLAMINO-(1H-INDOL-3-YL)-ACETIC ACID;(S)-TERT-BUTOXYCARBONYLAMINO-(1H-INDOL-3-YL)-ACETIC ACID;2-{[(tert-butoxy)carbonyl]amino}-2-(1H-indol-3-yl)acetic acid;2-(tert-butoxycarbonyl)acetic acid;N-BOC-2-(INDOLE-3-YL)-DL-GLYCINE;335356-02-0;862972-37-0

Suppliers and Price of 2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
[(tert-Butoxycarbonyl)amino]-(1H-indol-3-yl)acetic acid 97%
1g
$ 304.00

Crysdot
2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)aceticacid 95+%
5g
$ 733.00

Crysdot
2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)aceticacid 95+%
1g
$ 277.00

Chemenu
2-((tert-butoxycarbonyl)amino)-2-(1H-indol-3-yl)aceticacid 95%
1g
$ 262.00

Chemenu
2-((tert-butoxycarbonyl)amino)-2-(1H-indol-3-yl)aceticacid 95%
5g
$ 692.00

Atlantic Research Chemicals
[(tert-Butoxycarbonyl)amino](1H-indol-3-yl)aceticacid 95%
250mgs:
$ 63.62

American Custom Chemicals Corporation
[(TERT-BUTOXYCARBONYL)AMINO](1H-INDOL-3-YL)ACETIC ACID 95.00%
5G
$ 1570.52

Alichem
2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)aceticacid
5g
$ 777.00

Alichem
2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)aceticacid
1g
$ 305.20

aablocks
N-Boc-(3-indole)glycine 97%
5g
$ 720.00

Total 19 raw suppliers

Chemical Property of 2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)acetic acid

Chemical Property:

Vapor Pressure:1.17E-11mmHg at 25°C
Refractive Index:1.611
Boiling Point:520.5°C at 760 mmHg
PKA:3.70±0.30(Predicted)
Flash Point:268.6°C
PSA：91.42000
Density:1.29g/cm³
LogP:3.20920
Storage Temp.:2-8°C
XLogP3:2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:290.12665706
Heavy Atom Count:21
Complexity:405

Purity/Quality:

97% ^*data from raw suppliers

[(tert-Butoxycarbonyl)amino]-(1H-indol-3-yl)acetic acid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(C1=CNC2=CC=CC=C21)C(=O)O

Technology Process of 2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)acetic acid

There total 8 articles about 2-((tert-Butoxycarbonyl)amino)-2-(1H-indol-3-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 110317-49-2
N-(tert-Butyloxycarbonyl)-2-(3-indolyl)glycin-methylester

: 58237-94-8
N-Boc-indol-3-ylglycine

Guidance literature:: With sodium hydroxide; In methanol; for 3h; Heating;
DOI:10.3987/COM-00-8887

Reference yield:

: C₂₀H₂₆N₂O₆

: 58237-94-8
N-Boc-indol-3-ylglycine

Guidance literature:: C₂₀H₂₆N₂O₆; With water; lithium hydroxide; In ethanol; at 20 ℃;

With oxalic acid; In ethanol; for 0.25h; Reagent/catalyst; Temperature; Solvent;

Reference yield:

: 18372-22-0
2-(3-indolyl)oxoacetic acid methyl ester

: 58237-94-8
N-Boc-indol-3-ylglycine

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / hydroxylamine hydrochloride; NaOAc / methanol; H₂O / 6 h / Heating

2: 74 percent / hydrogen; HCl / Pd/C / methanol / 5 h / 3102.89 Torr

3: 98 percent / triethylamine / CH₂Cl₂ / 2 h / 20 °C

4: 97 percent / NaOH / methanol / 3 h / Heating

With hydrogenchloride; sodium hydroxide; hydroxylamine hydrochloride; hydrogen; sodium acetate; triethylamine; palladium on activated charcoal; In methanol; dichloromethane; water; 1: Condensation / 2: Reduction / 3: Acylation / 4: Hydrolysis;
DOI:10.3987/COM-00-8887