methyl 4-[2-(aziridin-1-yl)-2-oxido-1,3,2-oxazaphospholidin-3-yl]-2-hydroxybenzoate

Base Information

Chemical Name:methyl 4-[2-(aziridin-1-yl)-2-oxido-1,3,2-oxazaphospholidin-3-yl]-2-hydroxybenzoate
CAS No.:6964-89-2
Molecular Formula:C₁₂H₁₅N₂O₅P
Molecular Weight:298.235
Hs Code.:

Synonyms:Benzoicacid, 4-[2-(1-aziridinyl)-1,3,2-oxazaphospholidin-3-yl]-2-hydroxy-, methylester, P-oxide; Salicylic acid,4-[2-(1-aziridinyl)-1,3,2-oxazaphospholidin-3-yl]-, methyl ester, P-oxide(7CI); 1,3,2-Oxazaphospholidine, benzoic acid deriv.; NSC 67044

Suppliers and Price of methyl 4-[2-(aziridin-1-yl)-2-oxido-1,3,2-oxazaphospholidin-3-yl]-2-hydroxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of methyl 4-[2-(aziridin-1-yl)-2-oxido-1,3,2-oxazaphospholidin-3-yl]-2-hydroxybenzoate

Chemical Property:

Vapor Pressure:1.02E-08mmHg at 25°C
Boiling Point:450.1°C at 760 mmHg
Flash Point:226°C
Density:1.52g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of methyl 4-[2-(aziridin-1-yl)-2-oxido-1,3,2-oxazaphospholidin-3-yl]-2-hydroxybenzoate

There total 2 articles about methyl 4-[2-(aziridin-1-yl)-2-oxido-1,3,2-oxazaphospholidin-3-yl]-2-hydroxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6950-58-9
2-hydroxy-4-(2-hydroxy-ethylamino)-benzoic acid methyl ester

: 6964-89-2
4-(2-aziridin-1-yl-2-oxo-2λ⁵-[1,3,2]oxazaphospholidin-3-yl)-2-hydroxy-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: POCl₃

2: CHCl₃

With trichlorophosphate; In chloroform;
DOI:10.1021/jo01056a073