5-Chloro-3-phenylantranyl

Base Information

• Chemical Name: 5-Chloro-3-phenylantranyl
• CAS No.: 7716-88-3
• Molecular Formula: C13H8ClNO
• Molecular Weight: 229.666
• Mol file: 7716-88-3.mol

Synonyms:5-Chloro-3-phenylantranyl

Chemical Property of 5-Chloro-3-phenylantranyl

Chemical Property:

• PSA: 26.03000
• LogP: 4.14820
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

5-Chloro-3-phenylbenzo[d]isoxazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Chloro-3-phenylantranyl

There total 2 articles about 5-Chloro-3-phenylantranyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-Hydroxy-5-chlorbenzophenonoxim (26965-44-6) → 5-chloro-3-phenylbenzisoxazole (7716-88-3)

Guidance literature:

With silica gel supported sodium carbonate; water; for 0.0666667h; Cooling; Microwave irradiation; neat (no solvent);

Reference yield:

5-chloro-2-hydroxy-benzophenone O-acetyl-oxime → 5-chloro-3-phenylbenzisoxazole (7716-88-3)

Guidance literature:

With pyridine; for 3h; Heating;

Reference yield: 84.0%

5-chloro-3-phenylbenzisoxazole (7716-88-3) + N-(4-methylphenyl)acetamidine (14277-01-1) → 3-chloro-10-methyl-5-phenylbenzo[4,5]imidazo[1,2-a]quinoline

Guidance literature:

With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; 1-butyl-3-methylimidazolium Tetrafluoroborate; at 140 ℃; for 24h; Inert atmosphere;

upstream raw materials:

2-Hydroxy-5-chlorbenzophenonoxim

Refernces