14277-01-1

Usage

Uses

Used in Pharmaceutical Industry:
Ethanimidamide, N-(4-methylphenyl)is used as a chemical intermediate for the synthesis of pharmaceuticals and other organic compounds. Its unique structure and reactivity make it a valuable component in the development of new drugs and medications.
Used in Agricultural Industry:
Ethanimidamide, N-(4-methylphenyl)may have potential uses in the field of agriculture as a pesticide or herbicide. Its chemical properties could be harnessed to control pests and weeds, contributing to more efficient and effective agricultural practices.
Safety Precautions:
Due to its potential hazards and reactivity, Ethanimidamide, N-(4-methylphenyl)should be handled and stored in accordance with proper safety procedures to ensure the safety of individuals and the environment.

Upstream product

• 625-77-4 N-acetylacetamide 
• 540-23-8 p-toluidine hydrochloride 
• 106-49-0 p-toluidine 
• 1000-84-6 O-ethyl acetimidate 
• 75-05-8 acetonitrile 

Downstream Products

• 74168-47-1 4-Methyl-5-(p-tolyl)-2,2,6,6-tetrakis(trifluoromethyl)-5,6-dihydro-2H-1,3,5-oxadiazin 
• 87356-72-7 2-methyl-6-phenyl-3-(p-tolyl)pyrimidine-4(3H)-one 
• 87356-58-9 2-methyl-3-(4-tolyl)-pyrimidin-4(3H)-one 
• 5310-17-8 N-(p-tolyl)ethanethioamide 
• 87356-80-7 6-Phenyl-2-((Z)-styryl)-3-p-tolyl-3H-pyrimidin-4-one 
• 1139921-57-5 6-methyl-2-benzylquinoline 
• 1002107-38-1 2-methyl-1-p-tolyl-1H-imidazole-5-carbaldehyde 

Relevant academic research and scientific papers

Practical Synthesis of Benzimidazo[1,2- A[quinolines via Rh(III)-Catalyzed C-H Activation Cascade Reaction from Imidamides and Anthranils

We report a novel and practical one-pot Rh(III)-catalyzed strategy to construct benzimidazo[1,2-a]quinolines from readily available imidamides and anthranils. The cascade reaction proceeds via a C-H amination-cyclization-cyclization process in ionic liquid without any additives and possesses simple operation, moderate-to-high yield, and broad substrate scope features, which will provide the reference for the construction of biologically active fused benzimidazoles.

Synthesis of indoles and quinazolines via additive-controlled selective C-H activation/annulation of N -arylamidines and sulfoxonium ylides

Selective synthesis of indole and quinazoline products was achieved through a precise control of the C-H activation/annulation by changing the additives from NaOAc to CuF2/CsOAc. This strategy constructs indole and quinazoline scaffolds efficie

Synthesis of 2-Substituted Quinolines via Rhodium(III)-Catalyzed C–H Activation of Imidamides and Coupling with Cyclopropanols

An efficient synthesis of 2-substituted quinolines from readily available cyclopropanols and imidamides has been developed, where the cyclopropanol acts as a C3 synthon. With the assistance of a bifunctional imidamide directing group, the reaction occurred via sequential C–H/C–C cleavage and C–C/C–N bond formation. (Figure presented.).

Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents

Several compounds of great pharmacological interest contain the triazole and imidazole rings. In order to find new drugs with antileishmanial activity we have synthesized and evaluated new imidazole and triazole compounds carrying either the carbaldehyde or the difluoromethylene functionalities against promastigote forms of Leishmania amazonensis. Among the compounds tested difluoromethylene azoles 4b and 8f have inhibited the parasite growth significantly. Our results show that the introduction of the difluoromethylene moieties has turned the inactive carbaldehydes into active antileishmanial compounds.

Synthesis and Biological Evaluation of 6-Substituted 3-Aryl-2-methyl-4(3H)-pyrimidones

6-Substituted 3-aryl-2-methyl-4(3H)-pyrimidones (III) have been prepared by the reaction of N-arylacetamidines (II) with various diplorophiles like ethyl propiolate, ethyl tetrolate and ethyl phenylpropiolate.The structure of the products has been confirm