(1,10)PHENANTHROLIN-5-YLAMINE

Base Information

• Chemical Name: (1,10)PHENANTHROLIN-5-YLAMINE
• CAS No.: 54258-41-2
• Molecular Formula: C12H9N3
• Molecular Weight: 195.224
• Hs Code.: 29339900
• Mol file: 54258-41-2.mol

Synonyms:5-Amino-1,10-phenanthroline;Amino-1,1,0-phenanthroline;(1,10)Phenanthrolin-5-ylamine;

Chemical Property of (1,10)PHENANTHROLIN-5-YLAMINE

Chemical Property:

• Vapor Pressure: 5.59E-08mmHg at 25°C
• Melting Point: 254-258 ºC
• Refractive Index: 1.796
• Boiling Point: 441.1 ºC at 760 mmHg
• PKA: 5.20±0.10(Predicted)
• Flash Point: 250.8 ºC
• PSA: 51.80000
• Density: 1.333 g/cm³
• LogP: 2.94640
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility.: DMSO (Sparingly), Methanol (Sparingly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,10-Phenanthrolin-5-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-41-43
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 1,10-Phenanthrolin-5-amine can be used in the synthesis of bis-[1,10]phenanthrolin-5-yl-pyromellitic diimide (Bphen-PMD), which can find applications in organic light-emitting devices. 1,10-Phenanthrolin-5-amine is a potential fluorescent label for DNA detection. 1,10-Phenanthrolin-5-amine is used as a mediator for glucose oxidase for development of biosensors and biofuel cells

Technology Process of (1,10)PHENANTHROLIN-5-YLAMINE

There total 6 articles about (1,10)PHENANTHROLIN-5-YLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

5-Nitro-1,10-phenanthroline (4199-88-6) → 1,10-phenanthroline-5-amine (54258-41-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 1h; under 2280.15 Torr;

DOI:10.1039/b611089d

Reference yield: 68.0%

5-nitro-phenanthroline (41148-68-9) → 1,10-phenanthroline-5-amine (54258-41-2)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; at 120 ℃; for 2h;

DOI:10.1002/asia.201300690

Reference yield:

1,10-Phenanthroline (66-71-7) → 1,10-phenanthroline-5-amine (54258-41-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 63 percent / conc. HNO₃, 18percent oleum / 2 h / 100 - 110 °C

2: 58 percent / SnCl₂, hydrochloric acid / 1 h / 80 - 90 °C

With hydrogenchloride; sulfuric acid; nitric acid; tin(ll) chloride;

DOI:10.1007/BF01474201

upstream raw materials:

5-Nitro-1,10-phenanthroline

1,10-Phenanthroline

5-nitro-phenanthroline

Downstream raw materials:

N'-(1'',10''-phenantroline-5''-yl)-N-(2'-ethylhexyl)-1,6,7,12-tetrakis-[4'(1'',1'',3'',3''-tetramethylbutyl)phenoxy]-perylene-3,4:9,10-tetracarboximide

bis(2,2′-bipyridine)(5-aminophenanthroline)ruthenium bis(hexafluorophosphate)

5-oxo-5-(1,10-phenanthrolin-5-ylamino)pentanoic acid

C₂₂H₂₃N₅O₂S

Refernces

• 1、 Villien, Mathilde,Deroo, Stéphanie,Gicquel, Etienne,Defrancq, Eric,Moucheron, Cécile,Kirsch-De Mesmaeker, Andrée,Dumy, Pascal. "The oxime bond formation as an efficient tool for the conjugation of ruthenium complexes to oligonucleotides and peptides". . p. 11299 - 11306. Retrieved 2007.
• 2、 Kaloyanov, Nikolay,Neykov, Mihail,Wesselinova, Diana W.,Dimitrov, Georgi D.. "Synthesis and biological activity of novel heavy metal complexes of 5-amino-1, 10-phenanthroline and 1,10-phenanthroline". . p. 1034 - 1041. Retrieved 2012.
• 3、 Meggers, Eric,Kusch, Dirk,Giese, Bernd. "An efficient synthesis of enantiomerically pure Δ- and Λ-ruthenium(II)-labelled oligonucleotides". . p. 640 - 652. Retrieved 1997.
• 4、 dos Santos, Cidália M.G.,McCabe, Thomas,Gunnlaugsson, Thorfinnur. "Selective fluorescent sensing of chloride". . p. 3135 - 3139. Retrieved 2007.
• 5、 Soo, Jin Lee,Doo, Ri Bae,Won, Seok Han,Shim, Sung Lee,Jong, Hwa Jung. "Different morphological organic-inorganic hybrid nanomaterials as fluorescent chemosensors and adsorbents for CuII ions". . p. 1559 - 1564. Retrieved 2008.
• 6、 -. "Ionic iridium (III) complex containing viologen units and preparation method and application thereof". Paragraph 0035-0036; 0040. . Retrieved 2021/04/03.
• 7、 Beley, Marc,Blanchard-Desce, Mireille,Chevreux, Sylviane,Gros, Philippe C.,Lawson-Daku, Latévi Max,Lemercier, Gilles,Mongin, Olivier,Moreau, Juliette,Rousset, Elodie. "Molecular engineering for optical properties of 5-substituted-1,10-phenanthroline-based Ru(ii) complexes". . p. 10119 - 10132. Retrieved 2021/08/03.