5-Chloro-3-fluoro-2-hydroxypyridine

Base Information

Chemical Name:5-Chloro-3-fluoro-2-hydroxypyridine
CAS No.:514797-96-7
Molecular Formula:C5H3ClFNO
Molecular Weight:147.53
Hs Code.:2933399090
UNII:U37313A71T
DSSTox Substance ID:DTXSID90476159
Nikkaji Number:J1.861.130I
Wikidata:Q27290631
Mol file:514797-96-7.mol

Synonyms:514797-96-7;5-Chloro-3-fluoropyridin-2-ol;5-CHLORO-3-FLUORO-2-HYDROXYPYRIDINE;5-CHLORO-3-FLUORO-2-PYRIDINONE;2(1H)-Pyridinone, 5-chloro-3-fluoro-;5-chloro-3-fluoro-1H-pyridin-2-one;U37313A71T;UNII-U37313A71T;5-CHLORO-3-FLUORO-2-PYRIDINOL;SCHEMBL2298700;5-Chloro-3-Fluoropyridine-2-Ol;AMY1676;DTXSID90476159;AKLNMOLGRGQMFY-UHFFFAOYSA-N;BCP21199;MFCD07375044;MFCD11052335;5-Chloro-3-fluoro-2(1H)-pyridinone;AKOS006284843;AKOS015848874;AB41032;CGA 302371;CS-W003760;DS-2849;SY003435;NS00067235;5-chloro-3-fluoro-1,2-dihydropyridin-2-one;A828613;J-517344;Q27290631

Suppliers and Price of 5-Chloro-3-fluoro-2-hydroxypyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Chloro-3-fluoro-2-hydroxypyridine
500mg
$ 65.00

TRC
5-Chloro-3-fluoro-2-hydroxypyridine
250mg
$ 55.00

SynChem
5-CHLORO-3-FLUORO-2-HYDROXYPYRIDINE 95%
1 g
$ 80.00

SynChem
5-CHLORO-3-FLUORO-2-PYRIDINONE 95%
1 g
$ 75.00

Matrix Scientific
5-Chloro-3-fluoropyridin-2-ol >95%
5g
$ 576.00

Matrix Scientific
5-Chloro-3-fluoropyridin-2-ol >95%
1g
$ 144.00

Crysdot
5-Chloro-3-fluoropyridin-2-ol 97%
25g
$ 311.00

Chemenu
5-Chloro-3-fluoropyridin-2-ol 97%
25g
$ 320.00

Chemenu
5-Chloro-3-fluoropyridin-2-ol 97%
5g
$ 130.00

Chemenu
5-Chloro-3-fluoropyridin-2-ol 97%
10g
$ 194.00

Total 25 raw suppliers

Chemical Property of 5-Chloro-3-fluoro-2-hydroxypyridine

Chemical Property:

Vapor Pressure:0.00864mmHg at 25°C
Melting Point:71℃
Refractive Index:1.552
Boiling Point:219℃
PKA:8.90±0.10(Predicted)
Flash Point:86℃
PSA：33.12000
Density:1.46
LogP:1.57970
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:146.9887196
Heavy Atom Count:9
Complexity:209

Purity/Quality:

98%min ^*data from raw suppliers

5-Chloro-3-fluoro-2-hydroxypyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=C(C(=O)NC=C1Cl)F

Technology Process of 5-Chloro-3-fluoro-2-hydroxypyridine

There total 2 articles about 5-Chloro-3-fluoro-2-hydroxypyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 89402-43-7
5-chloro-2,3-difluoropyridine

: 514797-96-7
5-chloro-3-fluoro-2(1H)-pyridinone

Guidance literature:: With sodium hydroxide; at 75 ℃; for 20h;
DOI:10.1002/1099-0690(200212)2002:24<4174::AID-EJOC4174>3.0.CO;2-6

Reference yield: 78.0%

: 89402-43-7
5-chloro-2,3-difluoropyridine

: 514797-96-7
5-chloro-3-fluoropyridin-2-ol

Guidance literature:: 5-chloro-2,3-difluoropyridine; With sodium hydroxide; water; Heating / reflux;

With hydrogenchloride; water; pH=1;

Reference yield: 91.0%

: 514797-96-7
5-chloro-3-fluoro-2(1H)-pyridinone

: 103999-77-5
2,5-dichloro-3-fluoropyridine

Guidance literature:: With trichlorophosphate; In N,N-dimethyl-formamide; at 130 ℃; for 2h;
DOI:10.1002/1099-0690(200212)2002:24<4174::AID-EJOC4174>3.0.CO;2-6