1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid

Base Information

Chemical Name:1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid
CAS No.:519151-74-7
Molecular Formula:C13H12FNO2
Molecular Weight:233.24
Hs Code.:2933990090
ChEMBL ID:CHEMBL2113925
DSSTox Substance ID:DTXSID90407483
Wikidata:Q82212755
Mol file:519151-74-7.mol

Synonyms:519151-74-7;1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid;1-(4-Fluoro-phenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid;OSM-S-04;1-(4-fluorophenyl)-2,5-dimethylpyrrole-3-carboxylic acid;CHEMBL2113925;OSM-S-4;SCHEMBL1979515;DTXSID90407483;UHSNGSYVRLIXCX-UHFFFAOYSA-N;1-(4-fluorophenyl)-2,5-dimethyl-pyrrole-3-carboxylic Acid;BDBM50543246;MFCD03479904;AKOS000114835;SB62922;BS-14090;CS-0218402;EN300-00867;A871125;J-503306;Z56839659;1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylicacid;1-(4-fluoro-phenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid, AldrichCPR

Suppliers and Price of 1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylicacid 95+%
1g
$ 402.00

Chemenu
1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylicacid 95%
1g
$ 380.00

American Custom Chemicals Corporation
1-(4-FLUORO-PHENYL)-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLIC ACID 95.00%
5G
$ 1168.42

American Custom Chemicals Corporation
1-(4-FLUORO-PHENYL)-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLIC ACID 95.00%
2.5G
$ 983.88

American Custom Chemicals Corporation
1-(4-FLUORO-PHENYL)-2,5-DIMETHYL-1H-PYRROLE-3-CARBOXYLIC ACID 95.00%
1G
$ 721.57

Alichem
1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylicacid
1g
$ 321.44

AK Scientific
1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylicacid
2.5g
$ 664.00

AK Scientific
1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylicacid
500mg
$ 289.00

Total 13 raw suppliers

Chemical Property of 1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid

Chemical Property:

Vapor Pressure:1.18E-06mmHg at 25°C
Refractive Index:1.566
Boiling Point:386.2°C at 760 mmHg
Flash Point:187.4°C
PSA：42.23000
Density:1.21g/cm³
LogP:2.93140
Storage Temp.:2-8°C
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:233.08520679
Heavy Atom Count:17
Complexity:289

Purity/Quality:

97% ^*data from raw suppliers

1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(N1C2=CC=C(C=C2)F)C)C(=O)O

Technology Process of 1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid

There total 1 articles about 1-(4-Fluorophenyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 318511-70-5
tert-butyl 2-acetyl-4-oxopentanoate

: 371-40-4
4-fluoroaniline

: 519151-74-7
2,5-dimethyl-1-(4-fluorophenyl)-1H-pyrrole-3-carboxylic acid

Guidance literature:: With water; toluene-4-sulfonic acid; In dimethyl sulfoxide; at 120 ℃; for 0.5h; Microwave irradiation;
DOI:10.1021/acs.jmedchem.0c00660

Reference yield:

: 519151-74-7
2,5-dimethyl-1-(4-fluorophenyl)-1H-pyrrole-3-carboxylic acid

: 217313-79-6
4-(aminomethyl)benzamidine hydrochloride

: 1312604-20-8
N-[(4-carbamimidoylphenyl)methyl]-1-(4-fluorophenyl)-2,5-dimethyl-pyrrole-3-carboxamide

Guidance literature:: With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; In dichloromethane; dimethyl sulfoxide; at 20 ℃; for 168h;

Reference yield:

: 10406-25-4
4-aminobenzyl cyanide

: 519151-74-7
2,5-dimethyl-1-(4-fluorophenyl)-1H-pyrrole-3-carboxylic acid

: 1402085-80-6
1-(4-fluorophenyl)-N-[[4-(N'-hydroxycarbamimidoyl)phenyl]methyl]-2,5-dimethyl-pyrrole-3-carboxamide

Guidance literature:: 4-aminobenzyl cyanide; 2,5-dimethyl-1-(4-fluorophenyl)-1H-pyrrole-3-carboxylic acid; With oxalyl dichloride; triethylamine; In dichloromethane; at 20 ℃; for 3h;

With hydroxylamine hydrochloride; In ethanol; dichloromethane; at 80 ℃; for 3h;