4-[2-(2-Pyridinyl)ethyl]phenol

Base Information

• Chemical Name: 4-[2-(2-Pyridinyl)ethyl]phenol
• CAS No.: 3767-85-9
• Molecular Formula: C13H13 N O
• Molecular Weight: 199.2484
• NSC Number: 130873
• DSSTox Substance ID: DTXSID40299456
• Nikkaji Number: J520.259K
• Wikidata: Q82041881
• ChEMBL ID: CHEMBL2135960
• Mol file: 3767-85-9.mol

Synonyms:MLS002920070;3767-85-9;4-[2-(2-Pyridinyl)ethyl]phenol;NSC130873;SCHEMBL1772721;CHEMBL2135960;DTXSID40299456;RZKWYCPJVXNMMC-UHFFFAOYSA-N;2-Stilbazole, 4'-hydroxydihydro-;4-[2-(2-Pyridinyl)ethyl]phenol #;NSC-130873;SMR001797667

Chemical Property of 4-[2-(2-Pyridinyl)ethyl]phenol

Chemical Property:

• Vapor Pressure: 0.000106mmHg at 25°C
• Boiling Point: 327.5°C at 760 mmHg
• Flash Point: 151.9°C
• Density: 1.141g/cm³
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 199.099714038
• Heavy Atom Count: 15
• Complexity: 175

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=NC(=C1)CCC2=CC=C(C=C2)O

Technology Process of 4-[2-(2-Pyridinyl)ethyl]phenol

There total 4 articles about 4-[2-(2-Pyridinyl)ethyl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(E)-4-(2-(pyridin-2-yl)vinyl)phenol (77377-07-2) → 4-(2-[2]pyridyl-ethyl)-phenol (3767-85-9)

Guidance literature:

With sodium hydroxide; sodium amalgam; water;

DOI:10.1021/ja01145a085

Reference yield:

α-picoline (109-06-8) → 4-(2-[2]pyridyl-ethyl)-phenol (3767-85-9)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid anhydride / und Erwaermen des Reaktionsprodukts mit wss.Salzsaeure

2: Raney nickel; methanol / 80 - 90 °C / 73550.8 Torr / Hydrogenation

With methanol; acetic anhydride; nickel;

DOI:10.1021/ja01145a085

Reference yield:

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → 4-(2-[2]pyridyl-ethyl)-phenol (3767-85-9)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid anhydride / und Erwaermen des Reaktionsprodukts mit wss.Salzsaeure

2: Raney nickel; methanol / 80 - 90 °C / 73550.8 Torr / Hydrogenation

With methanol; acetic anhydride; nickel;

DOI:10.1021/ja01145a085

upstream raw materials:

(E)-4-(2-(pyridin-2-yl)vinyl)phenol

α-picoline

4-hydroxy-benzaldehyde