(2-Amino-5-methylphenyl)(phenyl)methanone

Base Information

• Chemical Name: (2-Amino-5-methylphenyl)(phenyl)methanone
• CAS No.: 17852-28-7
• Molecular Formula: C14H13 N O
• Molecular Weight: 211.263
• Hs Code.: 2922399090
• European Community (EC) Number: 241-804-3
• UNII: 9XZG5K5ZJX
• DSSTox Substance ID: DTXSID40170498
• Nikkaji Number: J82.681B
• Wikidata: Q72439197
• ChEMBL ID: CHEMBL1557131
• Mol file: 17852-28-7.mol

Synonyms:(2-Amino-5-methylphenyl)(phenyl)methanone;17852-28-7;2-Amino-5-methylbenzophenone;2-Benzoyl-4-methylaniline;(2-amino-5-methylphenyl)-phenylmethanone;(2-Amino-5-methyl-phenyl)-phenyl-methanone;2-amino-5-methylphenyl phenyl ketone;9XZG5K5ZJX;5-Methyl-2-aminobenzophenone;EINECS 241-804-3;Methanone, (2-amino-5-methylphenyl)phenyl-;UNII-9XZG5K5ZJX;Cambridge id 5689346;Oprea1_607451;MLS000532863;2-Amino-5-methyl-benzophenone;SCHEMBL5383825;CHEMBL1557131;SCHEMBL20468548;DTXSID40170498;Benzophenone, 2-amino-5-methyl-;HMS2479G14;MFCD00156832;STL088543;AKOS001587793;SB34367;NCGC00245763-01;DS-15056;SMR000140301;CS-0039105;FT-0710129;(2-Amino-5-methylphenyl)(phenyl)methanone #;(2-AMINO-5-METHYLPHENYL)PHENYLMETHANONE;O10039;SR-01000390379;SR-01000390379-1;(2-Amino-5-methyl-phenyl)-phenyl-methanone, AldrichCPR;Z1263602199

Chemical Property of (2-Amino-5-methylphenyl)(phenyl)methanone

Chemical Property:

• Vapor Pressure: 7.75E-07mmHg at 25°C
• Melting Point: 64-66℃
• Boiling Point: 407.1°C at 760 mmHg
• Flash Point: 200°C
• PSA: 43.09000
• Density: 1.135
• LogP: 3.38940
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 211.099714038
• Heavy Atom Count: 16
• Complexity: 245

Purity/Quality:

96% ^*data from raw suppliers

(2-amino-5-methylphenyl)(phenyl)methanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)N)C(=O)C2=CC=CC=C2

Technology Process of (2-Amino-5-methylphenyl)(phenyl)methanone

There total 28 articles about (2-Amino-5-methylphenyl)(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-amino-5-methylbenzonitrile (5925-93-9) + phenylmagnesium bromide (100-58-3) → 2-amino-5-methylbenzophenone (17852-28-7)

Guidance literature:

With water; In tetrahydrofuran; diethyl ether; at 20 ℃; for 17.5h; Solvent; Temperature; Cooling with ice;

Reference yield: 93.0%

2,2'-(1,4-Phenylene)bis(7-methyl-5-phenyl-3H-1,3,4-benzotriazepine) → 2-amino-5-methylbenzophenone (17852-28-7)

Guidance literature:

With hydrogenchloride; water; at 100 ℃; for 2h;

Reference yield: 90.0%

N-(4-methylphenyl)benzamide (582-78-5) → 2-amino-5-methylbenzophenone (17852-28-7)

Guidance literature:

In water; Irradiation; sodium dodecyl sulfate micelles;

upstream raw materials:

N-(2-benzoyl-4-methylphenyl)benzamide

1-(5-methyl-2,3-diphenyl-1H-indol-1-yl)ethan-1-one

p-toluidine

benzoyl chloride

Downstream raw materials:

6-methyl-4-phenyl-1H-quinazolin-2-one

2-methyl-fluoren-9-one

2-hydroxy-5-methylbenzophenone

N-(2-benzoyl-4-methylphenyl)acetamide

Refernces

• 1、 -. "Lactam Compound, Preparation Method and Use thereof". Paragraph 0165. . Retrieved 2020/02/14.
• 2、 Li, Quanzhe,Yu, Liuzhu,Wei, Yin,Shi, Min. "Synthesis of Diiodinated All-Carbon 3,3′-Diphenyl-1,1′-spirobiindene Derivatives via Cascade Enyne Cyclization and Electrophilic Aromatic Substitution". supporting information. p. 9282 - 9296. Retrieved 2019/08/12.