Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI)

Base Information

Chemical Name:Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI)
CAS No.:527751-18-4
Molecular Formula:C7H13NO2
Molecular Weight:143.18362
Hs Code.:
Mol file:527751-18-4.mol

Synonyms:Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI)

Suppliers and Price of Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(1S,3R)-3-Amino-2,2-dimethylcyclobutanecarboxylicacid 95+%
1g
$ 1623.00

Chemenu
(1S,3R)-3-amino-2,2-dimethylcyclobutane-1-carboxylicacid 95%
1g
$ 1530.00

Total 3 raw suppliers

Chemical Property of Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI)

Chemical Property:

Boiling Point:245.4±33.0 °C(Predicted)
PKA:3.69±0.40(Predicted)
PSA：63.32000
Density:1.108±0.06 g/cm3(Predicted)
LogP:1.14470
Storage Temp.:2-8°C

Purity/Quality:

≥99% ^*data from raw suppliers

(1S,3R)-3-Amino-2,2-dimethylcyclobutanecarboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI)

There total 5 articles about Cyclobutanecarboxylic acid, 3-amino-2,2-dimethyl-, (1S,3R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 308287-84-5
Methyl (1S,3R)-(+)-3-acetamido-2,2-dimethylcyclobutanecarboxylate

: 527751-18-4,92772-95-7
(1S,3R)-3-amino-2,2-dimethylcyclobutan-1-carboxylic acid

Guidance literature:: With hydrogenchloride; Heating;
DOI:10.1016/S0957-4166(02)00823-6

Reference yield:

: 188918-50-5,188918-39-0,1392803-26-7
(1S,3R)-3-[(tert-butoxycarbonyl)amino]-2,2-dimethylcyclobutane-1-carboxylic acid

: 527751-18-4,92772-95-7
(1S,3R)-3-amino-2,2-dimethylcyclobutan-1-carboxylic acid

Guidance literature:: With trifluoroacetic acid; In dichloromethane;
DOI:10.1016/S0040-4039(97)00200-1

Reference yield:

: 22571-78-4
(+)-cis-pinononoic acid

: 527751-18-4,92772-95-7
(1S,3R)-3-amino-2,2-dimethylcyclobutan-1-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / (PhO)2P(O)N₃, Et₃N / Heating

2: 83 percent / NaBrO, water / dioxane / 3 h / 0 °C

3: TFA / CH₂Cl₂

With sodium hypobromide; diphenyl phosphoryl azide; water; triethylamine; trifluoroacetic acid; In 1,4-dioxane; dichloromethane;
DOI:10.1016/S0040-4039(97)00200-1