1-Methyl-1H-benzo[d]imidazol-5-ol

Base Information

Chemical Name:1-Methyl-1H-benzo[d]imidazol-5-ol
CAS No.:50591-22-5
Molecular Formula:C8H8N2O
Molecular Weight:148.164
Hs Code.:2933990090
European Community (EC) Number:825-554-8
DSSTox Substance ID:DTXSID80357029
Wikidata:Q82136716
Mol file:50591-22-5.mol

Synonyms:1-Methyl-1H-benzo[d]imidazol-5-ol;50591-22-5;1-Methyl-1h-benzimidazol-5-ol;1-methylbenzimidazol-5-ol;MFCD00456136;1-Methyl-5-hydroxybenzimidazole;1-methyl-1H-1,3-benzodiazol-5-ol;F2135-1036;SCHEMBL1496402;DTXSID80357029;NDDDURSMVVKBTL-UHFFFAOYSA-N;AR2759;AKOS003662853;1H-Benzimidazol-5-ol,1-methyl-(9CI);DS-17782;SY104270;BB 0260600;CS-0043996;EN300-192223;A871511;AT-057/40152698;Z275242686

Suppliers and Price of 1-Methyl-1H-benzo[d]imidazol-5-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Methyl-1H-benzimidazol-5-ol
500mg
$ 175.00

Matrix Scientific
1-Methyl-1H-benzimidazol-5-ol 95%+
1g
$ 393.00

Matrix Scientific
1-Methyl-1H-benzimidazol-5-ol 95%+
5g
$ 1298.00

Matrix Scientific
1-Methyl-1H-benzimidazol-5-ol 95%+
2.500g
$ 857.00

Crysdot
1-Methyl-1H-benzo[d]imidazol-5-ol 95+%
10g
$ 798.00

Crysdot
1-Methyl-1H-benzo[d]imidazol-5-ol 95+%
5g
$ 410.00

Crysdot
1-Methyl-1H-benzo[d]imidazol-5-ol 95+%
25g
$ 1921.00

Chemenu
1-Methyl-1H-benzimidazol-5-ol 98%
1000g
$ 12160.00

ChemBridge Corporation
1-methyl-1H-benzimidazol-5-ol 95%
1 g
$ 235.00

Apolloscientific
1-Methyl-1H-benzimidazol-5-ol 98%
250mg
$ 218.00

Total 19 raw suppliers

Chemical Property of 1-Methyl-1H-benzo[d]imidazol-5-ol

Chemical Property:

Boiling Point:337.7±34.0 °C(Predicted)
PKA:8.90±0.40(Predicted)
PSA：38.05000
Density:1.27±0.1 g/cm3(Predicted)
LogP:1.27890
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:148.063662883
Heavy Atom Count:11
Complexity:151

Purity/Quality:

99%, ^*data from raw suppliers

1-Methyl-1H-benzimidazol-5-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=NC2=C1C=CC(=C2)O
Uses 1-methyl-1H-benzimidazol-5-ol is a useful reactant for the preparation of substituted azaquinazolinones as modulators of GHSr-1a for the treatment of type II diabetes and obesity

Technology Process of 1-Methyl-1H-benzo[d]imidazol-5-ol

There total 10 articles about 1-Methyl-1H-benzo[d]imidazol-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

: 10394-39-5
5-methoxy-1-methyl-1H-benzo[d]imidazole

: 50591-22-5
1-methyl-1H-benzo[d]imidazol-5-ol

Guidance literature:: With hydrogen bromide; acetic acid; at 110 ℃; for 48h;

Reference yield:

: 4887-80-3
5-methoxy-1H-benzimidazole

: 50591-22-5
1-methyl-1H-benzo[d]imidazol-5-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 27 °C

1.2: 16 h

2.1: boron tribromide / dichloromethane / 2 h / 0 °C

With boron tribromide; sodium hydride; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 3360-79-0
N-methyl-4-methoxy-2-nitroaniline

: 50591-22-5
1-methyl-1H-benzo[d]imidazol-5-ol

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen; palladium on activated charcoal / ethanol; tetrahydrofuran / 4 h / 20 °C

2: 2-methoxy-ethanol / 20 h / 120 °C

3: acetic acid; hydrogen bromide / 48 h / 110 °C

With palladium on activated charcoal; hydrogen bromide; hydrogen; acetic acid; In tetrahydrofuran; ethanol; 2-methoxy-ethanol;