Methyl 3,4-diamino-2-methoxybenzoate

Base Information

Chemical Name:Methyl 3,4-diamino-2-methoxybenzoate
CAS No.:538372-37-1
Molecular Formula:C9H12N2O3
Molecular Weight:196.206
Hs Code.:2922509090
European Community (EC) Number:847-784-8
DSSTox Substance ID:DTXSID40477515
Wikidata:Q82310271
Mol file:538372-37-1.mol

Synonyms:Methyl 3,4-diamino-2-methoxybenzoate;538372-37-1;Benzoic acid, 3,4-diamino-2-methoxy-, methyl ester (9CI);Benzoic acid, 3,4-diamino-2-methoxy-, methyl ester;SCHEMBL5553956;DTXSID40477515;AMY14753;Methyl3,4-diaMino-2-Methoxybenzoate;MFCD18970771;AKOS022173248;DS-7266;CS-0061932;Methyl 3 pound not4-diamino-2-methoxybenzoate;I11076;A870624;Benzoic acid,3,4-diamino-2-methoxy-,methyl ester(9ci)

Suppliers and Price of Methyl 3,4-diamino-2-methoxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
Methyl3,4-Diamino-2-methoxybenzoate
25 mg
$ 610.00

Labseeker
Benzoicacid,3,4-diamino-2-methoxy-,methylester(9CI) 95
100g
$ 7000.00

Crysdot
Methyl3,4-diamino-2-methoxybenzoate 98%
1g
$ 450.00

Crysdot
Methyl3,4-diamino-2-methoxybenzoate 98%
250mg
$ 142.00

Chemenu
methyl3,4-diamino-2-methoxybenzoate 95+%
5g
$ 1017.00

Chemenu
methyl3,4-diamino-2-methoxybenzoate 95+%
1g
$ 337.00

Ambeed
Methyl3,4-diamino-2-methoxybenzoate 98%
250mg
$ 315.00

Ambeed
Methyl3,4-diamino-2-methoxybenzoate 98%
100mg
$ 198.00

Ambeed
Methyl3,4-diamino-2-methoxybenzoate 98%
50mg
$ 145.00

Ambeed
Methyl3,4-diamino-2-methoxybenzoate 98%
1g
$ 495.00

Total 12 raw suppliers

Chemical Property of Methyl 3,4-diamino-2-methoxybenzoate

Chemical Property:

Boiling Point:408.6±40.0 °C(Predicted)
PKA:2.96±0.10(Predicted)
PSA：87.57000
Density:1.258±0.06 g/cm3(Predicted)
LogP:1.80860
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Solubility.:DCM, Deuterated Chloroform, Methanol
XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:196.08479225
Heavy Atom Count:14
Complexity:210

Purity/Quality:

97% ^*data from raw suppliers

Methyl3,4-Diamino-2-methoxybenzoate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1N)N)C(=O)OC
Uses Methyl 3,4-Diamino-2-methoxybenzoate is a widely used reactant in the synthesis of DNA-binding oligomers.

Technology Process of Methyl 3,4-diamino-2-methoxybenzoate

There total 4 articles about Methyl 3,4-diamino-2-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 457947-61-4
4-amino-5-chloro-2-methoxy-3-nitro-benzoic acid methyl ester

: 538372-37-1
3,4-diamino-2-methoxy-benzoic acid methyl ester

Guidance literature:: With palladium on activated charcoal; triethylamine; In methanol; for 16h; under 3040.2 Torr; Inert atmosphere;

Reference yield:

: 4093-31-6
methyl 2-methoxy 4-acetamido 5-chloro benzoate

: 538372-37-1
3,4-diamino-2-methoxy-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / HNO₃ / 0.17 h / 20 °C

2: 94 percent / aq. H₂SO₄ / methanol / 9 h / Heating

3: H₂; Et₃N / Pd/C / 6 h / 3800 Torr

With sulfuric acid; hydrogen; nitric acid; triethylamine; palladium on activated charcoal; In methanol;
DOI:10.1021/ja0300158

Reference yield:

: 126463-85-2
4-acetylamino-5-chloro-2-methoxy-3-nitro-benzoic acid methyl ester

: 538372-37-1
3,4-diamino-2-methoxy-benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / aq. H₂SO₄ / methanol / 9 h / Heating

2: H₂; Et₃N / Pd/C / 6 h / 3800 Torr

With sulfuric acid; hydrogen; triethylamine; palladium on activated charcoal; In methanol;
DOI:10.1021/ja0300158