5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole

Base Information

Chemical Name:5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole
CAS No.:59562-68-4
Molecular Formula:C9H7FN2O
Molecular Weight:178.166
Hs Code.:2934999090
DSSTox Substance ID:DTXSID80485730
Wikidata:Q82325170
Mol file:59562-68-4.mol

Synonyms:5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole;59562-68-4;5-(4-FLUORO-PHENYL)-3-METHYL-[1,2,4]OXADIAZOLE;SCHEMBL4668357;DTXSID80485730;YTSHBDOOEVBVHX-UHFFFAOYSA-N;AKOS006282369;MB07185;BS-29248

Suppliers and Price of 5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole
500mg
$ 185.00

Crysdot
5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole 95+%
5g
$ 452.00

Apolloscientific
5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole 98%
5g
$ 595.00

Apolloscientific
5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole 98%
1g
$ 160.00

Total 5 raw suppliers

Chemical Property of 5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole

Chemical Property:

PSA：38.92000
LogP:2.18410
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:178.05424101
Heavy Atom Count:13
Complexity:171

Purity/Quality:

99% ^*data from raw suppliers

5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NOC(=N1)C2=CC=C(C=C2)F
Uses 5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole

Technology Process of 5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole

There total 4 articles about 5-(4-Fluorophenyl)-3-methyl-1,2,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 403-43-0
4-fluorobenzoyl chloride

: 118493-85-9,117771-39-8,1141922-26-0,1429624-21-4
acetamide oxime

: 59562-68-4
3-methyl-5-(4'-fluorophenyl)-1,2,4-oxadiazole

Guidance literature:: 4-fluorobenzoyl chloride; acetamide oxime; With potassium carbonate; In acetone; at 20 ℃; for 1.5h;

at 130 ℃; for 1.5h; Sealed tube;
DOI:10.1016/j.ejmech.2013.03.069

Reference yield:

: 459-46-1
4-Fluorobenzyl bromide

: 59562-68-4
3-methyl-5-(4'-fluorophenyl)-1,2,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: methanol

2: Zn, AcOH

With acetic acid; zinc; In methanol;
DOI:10.1021/jo00880a013

Reference yield:

: 403-43-0
4-fluorobenzoyl chloride

: 59562-68-4
3-methyl-5-(4'-fluorophenyl)-1,2,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone

2: Heating

With potassium carbonate; In acetone;
DOI:10.1016/j.bmc.2014.10.037