Methyl 14-oxopentadecanoate

Base Information

• Chemical Name: Methyl 14-oxopentadecanoate
• CAS No.: 54889-71-3
• Molecular Formula: C₁₆H₃₀O₃
• Molecular Weight: 270.412
• Hs Code.: 2918300090
• Mol file: 54889-71-3.mol

Synonyms:Methyl 14-oxopentadecanoate

Chemical Property of Methyl 14-oxopentadecanoate

Chemical Property:

• PSA: 43.37000
• LogP: 4.42960

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 14-oxopentadecanoate

There total 6 articles about Methyl 14-oxopentadecanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(-)-(R)-14-Hydroxypentadecansaeure-methylester (88785-28-8) → 14-oxo-pentadecanoic acid methyl ester (54889-71-3)

Guidance literature:

With sodium dichromate; acetic acid; In benzene; at 60 - 70 ℃;

Reference yield:

C17H29BrMgO3 → 14-oxo-pentadecanoic acid methyl ester (54889-71-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 52 percent / (CH₃)2S*Cu(I)Br / tetrahydrofuran / 4 h / -30 °C

2: 1) 0.02N H₂SO₄; 2) 2N KOH / ethyl acetate; dioxane / 1 h / Heating; 1) reflux, 30 min; 2) reflux, 30 min

With potassium hydroxide; copper(I) bromide dimethylsulfide complex; sulfuric acid; In tetrahydrofuran; 1,4-dioxane; ethyl acetate;

DOI:10.1002/hlca.19830660741

Reference yield:

14-(2,4,10-Trioxatricyclo<3.3.1.13,7>dec-3-yl)-2-tetradecanon (88785-15-3) → 14-oxo-pentadecanoic acid methyl ester (54889-71-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) 0.02N H₂SO₄; 2) 2N KOH / ethyl acetate; dioxane / 1 h / Heating; 1) reflux, 30 min; 2) reflux, 30 min

With potassium hydroxide; sulfuric acid; In 1,4-dioxane; ethyl acetate;

DOI:10.1002/hlca.19830660741

upstream raw materials:

methylene chloride

14-oxopentadecanoic acid

(-)-(R)-14-Hydroxypentadecansaeure-methylester

methanol

Refernces

• 1、 Voss, Gundula,Gerlach, Hans. "Orthocarbonsaeure-ester mit 2,4,10-Trioxaadamantanstruktur als Carboxylschutzgruppe; Verwendung zur Synthese von substituierten Carbonsaeuren mit Hilfe von Grignard-Reagenzien". . p. 2294 - 2307. Retrieved 2007/10/02.