1-Phenylpiperazine-2,3-dione

Base Information

Chemical Name:1-Phenylpiperazine-2,3-dione
CAS No.:59702-39-5
Molecular Formula:C₁₀H₁₀N₂O₂
Molecular Weight:190.202
Hs Code.:
DSSTox Substance ID:DTXSID90501910
Mol file:59702-39-5.mol

Synonyms:1-Phenylpiperazine-2,3-dione;59702-39-5;SCHEMBL6224361;DTXSID90501910;AKOS006332034

Suppliers and Price of 1-Phenylpiperazine-2,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-PHENYLPIPERAZINE-2,3-DIONE 95.00%
5MG
$ 496.45

Total 2 raw suppliers

Chemical Property of 1-Phenylpiperazine-2,3-dione

Chemical Property:

Refractive Index:1.578
PSA：49.41000
Density:1.261g/cm³
LogP:0.54320
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:190.074227566
Heavy Atom Count:14
Complexity:247

Purity/Quality:

99% ^*data from raw suppliers

1-PHENYLPIPERAZINE-2,3-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(C(=O)C(=O)N1)C2=CC=CC=C2

Technology Process of 1-Phenylpiperazine-2,3-dione

There total 4 articles about 1-Phenylpiperazine-2,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1664-40-0
N-(2-aminoethyl)benzeneamine

: 59702-39-5
1-phenyl-piperazine-2,3-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 2.) Et₃N / 1.) CH₂Cl₂, 0 deg C, 2.) 45 min

2: 100 percent / HCl gas / ethyl acetate / 0.05 h / 0 °C

3: acetophenone, Na(OAc)3BH, 4A MS / 1,2-dichloro-ethane / 1.) 0 deg C, 30 min, 2.) room temperature, 4 h

With hydrogenchloride; sodium tris(acetoxy)borohydride; triethylamine; acetophenone; In ethyl acetate; 1,2-dichloro-ethane;
DOI:10.1021/jo9800309

Reference yield:

: 206753-50-6
N-(2-tert-Butoxycarbonylamino-ethyl)-N-phenyl-oxalamic acid methyl ester

: 59702-39-5
1-phenyl-piperazine-2,3-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / HCl gas / ethyl acetate / 0.05 h / 0 °C

2: acetophenone, Na(OAc)3BH, 4A MS / 1,2-dichloro-ethane / 1.) 0 deg C, 30 min, 2.) room temperature, 4 h

With hydrogenchloride; sodium tris(acetoxy)borohydride; acetophenone; In ethyl acetate; 1,2-dichloro-ethane;
DOI:10.1021/jo9800309

Reference yield:

: N-(2-Amino-ethyl)-N-phenyl-oxalamic acid methyl ester; hydrochloride

: N-(2-Phenylamino-ethyl)-oxalamic acid methyl ester

: 59702-39-5
1-phenyl-piperazine-2,3-dione

Guidance literature:: With sodium tris(acetoxy)borohydride; acetophenone; In 1,2-dichloro-ethane; Yield given. Yields of byproduct given; 1.) 0 deg C, 30 min, 2.) room temperature, 4 h;
DOI:10.1021/jo9800309