Technology Process of 2-(Pyridin-3-yl)ethane-1-thiol
There total 5 articles about 2-(Pyridin-3-yl)ethane-1-thiol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-pyridylethyl thioacetate;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 60 ℃;
for 3h;
Inert atmosphere;
Cooling with ice;
With
water; acetic acid;
In
tetrahydrofuran;
Cooling with ice;
With
sodium hydrogencarbonate;
In
tetrahydrofuran; water; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: ethanol; water / 4 h / Inert atmosphere; Reflux
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 60 °C / Inert atmosphere; Cooling with ice
2.2: Cooling with ice
With
lithium aluminium tetrahydride;
In
tetrahydrofuran; ethanol; water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: thionyl chloride / chloroform / 3 h / 20 °C / Inert atmosphere
2.1: ethanol; water / 4 h / Inert atmosphere; Reflux
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 60 °C / Inert atmosphere; Cooling with ice
3.2: Cooling with ice
With
lithium aluminium tetrahydride; thionyl chloride;
In
tetrahydrofuran; ethanol; chloroform; water;
