4-(5-methoxycarbonylthiophen-2-yl)benzoic Acid

Base Information

Chemical Name:4-(5-methoxycarbonylthiophen-2-yl)benzoic Acid
CAS No.:597565-50-9
Molecular Formula:C12H8O4S
Molecular Weight:248.259
Hs Code.:
DSSTox Substance ID:DTXSID00408289
Wikidata:Q82213719
Mol file:597565-50-9.mol

Synonyms:4-(5-methoxycarbonylthiophen-2-yl)benzoic Acid;597565-50-9;DTXSID00408289

Suppliers and Price of 4-(5-methoxycarbonylthiophen-2-yl)benzoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-(4-Carboxy-phenyl)-thiophene-2-carboxylicacid 95%+
1g
$ 590.00

Advanced Chemicals Intermediatesced Chemicals Intermediates
5-(4-Carboxy-phenyl)-thiophene-2-carboxylicacid 95%+
1g
$ 282.75

Acints
5-(4-Carboxy-phenyl)-thiophene-2-carboxylicacid 95%+
10g
$ 1732.75

Acints
5-(4-Carboxy-phenyl)-thiophene-2-carboxylicacid 95%+
5g
$ 978.75

Acints
5-(4-Carboxy-phenyl)-thiophene-2-carboxylicacid 95%+
1g
$ 282.75

Total 1 raw suppliers

Chemical Property of 4-(5-methoxycarbonylthiophen-2-yl)benzoic Acid

Chemical Property:

Boiling Point:508.1±45.0 °C(Predicted)
PKA:3.32±0.10(Predicted)
PSA：91.84000
Density:1.466±0.06 g/cm3(Predicted)
LogP:2.89990
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:262.02997997
Heavy Atom Count:18
Complexity:323

Purity/Quality:: 5-(4-Carboxy-phenyl)-thiophene-2-carboxylicacid 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC=C(S1)C2=CC=C(C=C2)C(=O)O

Technology Process of 4-(5-methoxycarbonylthiophen-2-yl)benzoic Acid

There total 2 articles about 4-(5-methoxycarbonylthiophen-2-yl)benzoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 7311-63-9
5-bromothiophene-2-carboxylic acid

: 14047-29-1
4-carboxyphenylboronic acid

: 597565-50-9
5-(4-carboxyphenyl)-2-thiophenecarboxylic acid

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; Davisil 500 Angstroem beads; sodium carbonate; In water; for 3h; Heating;
DOI:10.1016/S0040-4039(03)01128-6

Reference yield: 21.0%

: 527-72-0
2-thiophenylcarboxylic acid

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 597565-50-9
5-(4-carboxyphenyl)-2-thiophenecarboxylic acid

Guidance literature:: 4-amino-benzoic acid; With hydrogenchloride; sodium nitrite; In water; at 5 ℃; for 0.333333h;

2-thiophenylcarboxylic acid; In water; acetone; at 20 ℃; for 48h;
DOI:10.3390/80300342