Refernces
10.1039/c6cc00713a
The study presents an efficient palladium-catalyzed silylation reaction between benzylic halides and silyboronate, which allows for the synthesis of benzylic silanes. The reaction accommodates a broad substrate scope and proceeds under mild conditions, yielding products with moderate to high yields and stereospecificity. Key chemicals used include primary and secondary benzylic halides, silyboronates, and palladium catalysts such as Pd(PPh3)4, along with silver oxide (Ag2O) as a co-catalyst. These chemicals serve the purpose of facilitating the formation of C-Si bonds, which are important in the synthesis of bioactive molecules and organic materials. The study also explores the reaction's mechanism and demonstrates that it can be used for the synthesis of various benzyl silane compounds, including those with sensitive functional groups, and maintains enantiopurity in enantioenriched substrates.
10.1039/P19910003033
The research focuses on the synthesis of phenanthrene-2,7-quinone derivatives, which are complex organic compounds with potential applications in various chemical and pharmaceutical fields. The study aims to develop methods for synthesizing these quinones, which are challenging to isolate due to their instability. The researchers used a variety of chemicals in their experiments, including 2,2',4,4'-tetramethoxystilbene-3,3'-diol, silver oxide, potassium ferricyanide, and various derivatives of phenanthrene. They successfully synthesized several stable phenanthrenequinones, such as 1,3,6,8-tetramethoxyphenanthrene-2,7-quinone and 9,10-dihydrophenanthrene-2,7-quinone, and discussed the challenges in synthesizing others, like 1,6-, 2,7-, and 3,6-quinones. The conclusions highlight the effectiveness of methoxy groups in increasing the stability of non-aromatic polycyclic quinones and the potential for these compounds to be considered as vinylogous esters.
10.1002/anie.201914151
The research focuses on the development of highly efficient asymmetric intermolecular radical-polar crossover reactions between indanonecarboxamides/ester and various electron-rich alkenes. The purpose of this study was to achieve this through the combination of a chiral N,N′-dioxide-NiII complex catalyst with Ag2O under mild reaction conditions. The conclusion of the research was the successful synthesis of a wide range of chiral spirocycles containing a quaternary all-carbon stereocenter, as well as four special functionalized products such as alkenes, aldehydes, ketones, and alcohols, all with good to excellent yields and enantioselectivities.
10.1016/0008-6215(83)88138-5
The research investigates the cleavage of interglycosidic linkages in per(trimethylsilyl)ated and permethylated carbohydrates using iodotrimethylsilane (ITMS) in carbon tetrachloride. The purpose of the study was to develop a rapid and mild method for the hydrolysis of carbohydrate chains, which could be particularly useful in the analysis of permethylated carbohydrates. The conclusions drawn from the research indicate that ITMS is more reactive towards interglycosidic linkages in permethylated carbohydrates compared to per(trimethylsilyl)ated ones, and that the cleavage rate depends on the type of interglycosidic linkage. The study found that iodinolysis with ITMS, followed by treatment with water, offers a novel method for hydrolysis of permethylated carbohydrates. Key chemicals used in the process include iodotrimethylsilane, carbon tetrachloride, methanol, silver oxide, and various permethylated and per(trimethylsilyl)ated mono- and disaccharides.