tris(4-methoxyphenyl) phosphite

Base Information

• Chemical Name: tris(4-methoxyphenyl) phosphite
• CAS No.: 19909-81-0
• Molecular Formula: C21H21 O6 P
• Molecular Weight: 400.368
• Mol file: 19909-81-0.mol

Synonyms:Phenol,p-methoxy-, phosphite (3:1) (8CI); Tri(4-methoxyphenyl) phosphite;Tri(p-methoxyphenyl) phosphite; Tri-p-anisyl phosphite; Tris(4-methoxyphenyl)phosphite; Tris(p-methoxyphenyl) phosphite; tris(p-Methoxyphenyl) phosphite

Chemical Property of tris(4-methoxyphenyl) phosphite

Chemical Property:

• Vapor Pressure: 1.5E-08mmHg at 25°C
• Boiling Point: 469.9°C at 760 mmHg
• Flash Point: 296.7°C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tris(4-methoxyphenyl) phosphite

There total 4 articles about tris(4-methoxyphenyl) phosphite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-methoxy-phenol (150-76-5) → tris(p-methoxyphenyl)phosphite (19909-81-0)

Guidance literature:

With pyridine; phosphorus tribromide; In diethyl ether; at 20 ℃; Inert atmosphere;

DOI:10.1021/ol900240s

Reference yield: 37.0%

4-methoxy-phenol (150-76-5) → tris(p-methoxyphenyl)phosphite (19909-81-0) + Tris-(4-methoxyphenyl) phosphate (3862-09-7)

Guidance literature:

With potassium phosphate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; diphenyl diselenide; phosphorus; In dimethyl sulfoxide; toluene; at 60 ℃; for 4h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.1c01695

Reference yield:

p-methoxyphenyl phosphorodichloridite (135263-41-1) → tris(p-methoxyphenyl)phosphite (19909-81-0)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / hexane / -30 - 22 °C / Inert atmosphere

2: 336 h / 20 - 22 °C / Inert atmosphere

With triethylamine; In hexane;

DOI:10.1134/S1070363220050138

upstream raw materials:

4-methoxy-phenol

p-methoxyphenyl phosphorodichloridite

Downstream raw materials:

(RS)-3-amino-3-phenyl-propionic acid hydrochloride

p-Nitrobenzyl 7-amino-3-methyl-3-cephem-4-carboxylate, hydrochloride salt

C₂₉H₂₇N₂O₉P